Synthesis and characterization of anti-infective agents [PDF]
Antifungal chemotherapy depends on bio-chemical alterations between fungi and mammals. Unlike bacteria, which are prokaryotes, both fungi and mammals are eukaryotes and the biochemical differences between them are not significant. However, there are some
Monika Sharma+5 more
doaj +4 more sources
Evaluation of Triazole and Isoxazole Derivatives as Potential Anti-infective Agents. [PDF]
Tarawneh AH+7 more
europepmc +3 more sources
Penetration of Anti-Infective Agents into Pulmonary Epithelial Lining Fluid [PDF]
Epithelial lining fluid (ELF) is often considered to be the site of extracellular pulmonary infections. During the past 25 years, a limited number of studies have evaluated the intrapulmonary penetration of antifungal, antitubercular, antiparasitic and antiviral agents. For antifungal agents, differences in drug concentrations in ELF or bronchoalveolar
Keith A. Rodvold, Jomy George, Liz Yoo
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AbOmpA in Acinetobacter baumannii: exploring virulence mechanisms of outer membrane-integrated and outer membrane vesicle-associated AbOmpA and developing anti-infective agents targeting AbOmpA. [PDF]
Oh MH+6 more
europepmc +2 more sources
Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis. [PDF]
Forde E+4 more
europepmc +2 more sources
The status surrounding chloroquine and other drugs as potential anti-infective agents for COVID-19. [PDF]
Ramotar D.
europepmc +3 more sources
Limited-sampling strategies for anti-infective agents: systematic review. [PDF]
Sprague DA, Ensom MH.
europepmc +3 more sources
Resistance to colistin, one of the antibiotics of last resort against multidrug-resistant Gram-negative bacteria, is increasingly reported. Notably, MCR plasmids discovered in 2015 have now been reported worldwide in humans.
Chantal Valcourt+5 more
doaj +1 more source
Immunosuppressive drug interactions with anti-infective agents [PDF]
openalex +4 more sources
Comparison between Colistin Sulfate Dry Powder and Solution for Pulmonary Delivery
To assess the difference in the fate of the antibiotic colistin (COLI) after its pulmonary delivery as a powder or a solution, we developed a COLI powder and evaluated the COLI pharmacokinetic properties in rats after pulmonary administration of the ...
Frédéric Tewes+7 more
doaj +1 more source