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Hybrid Compounds as Anti-infective Agents
Hybrid drugs are multi-target chimeric chemicals combining two or more drugs or pharmacophores covalently linked in a single molecule. In the field of anti-infective agents, they have been proposed as a possible solution to drug resistance issues, presumably having a broader spectrum of activity and less probability of eliciting high level resistance ...
María L. Sbaraglini, Alan Talevi
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Editorial: Inspired by Nature: Towards Novel Anti-Infective Agents [PDF]
Ricardo J. Ferreira +5 more
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The Role of Pathogens and Anti-Infective Agents in Parkinson’s Disease, from Etiology to Therapeutic Implications [PDF]
Si Shen +3 more
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AbOmpA in Acinetobacter baumannii: exploring virulence mechanisms of outer membrane-integrated and outer membrane vesicle-associated AbOmpA and developing anti-infective agents targeting AbOmpA [PDF]
Man-Hwan Oh +6 more
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Pharmacokinetic Drug–Drug Interactions Between Immunosuppressant and Anti-Infective Agents: Antimetabolites and Corticosteroids [PDF]
Edward T. Van Matre +5 more
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Mannose Derivatives as Anti-Infective Agents [PDF]
Rosana Ribić
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Resistance to colistin, one of the antibiotics of last resort against multidrug-resistant Gram-negative bacteria, is increasingly reported. Notably, MCR plasmids discovered in 2015 have now been reported worldwide in humans.
Chantal Valcourt +5 more
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