Results 11 to 20 of about 119,511 (340)

Small and Versatile Cyclotides as Anti-infective Agents. [PDF]

ACS Infect Dis
Plants provide an abundant source of potential therapeutic agents, including a diverse array of compounds, such as cyclotides, which are peptides known for their antimicrobial activity. Cyclotides are multifaceted molecules with a wide range of biological activities.
Cândido ES, Gasparetto LS, Luchi LV, Pimentel JPF, Cardoso MH, Macedo MLR, de la Fuente-Nunez C, Franco OL.   +7 more
europepmc   +4 more sources

AbOmpA in Acinetobacter baumannii: exploring virulence mechanisms of outer membrane-integrated and outer membrane vesicle-associated AbOmpA and developing anti-infective agents targeting AbOmpA. [PDF]

J Biomed Sci
Oh MH, Islam MM, Kim N, Choi CH, Shin M, Shin WS, Lee JC.   +6 more
europepmc   +2 more sources

Design and Synthesis of Ketoconazole Derivatives as Innovative Anti-Infective Agents. [PDF]

Arch Pharm (Weinheim)
Renzi G, Angeli A, Selleri S, Spadini C, Mezzasalma N, Hull MT, Kelly SL, Capasso C, Cabassi CS, Carta F, Supuran CT.   +10 more
europepmc   +2 more sources

VITAMIN A AS AN ANTI-INFECTIVE AGENT [PDF]

BMJ, 1928
H. N. Green, E. Mellanby
openalex   +4 more sources

The status surrounding chloroquine and other drugs as potential anti-infective agents for COVID-19. [PDF]

Expert Rev Respir Med, 2020
Ramotar D.
europepmc   +3 more sources

Potential of host defense peptide prodrugs as neutrophil elastase-dependent anti-infective agents for cystic fibrosis. [PDF]

Antimicrob Agents Chemother, 2014
Forde E, Humphreys H, Greene CM, Fitzgerald-Hughes D, Devocelle M.   +4 more
europepmc   +2 more sources

Lipid Nanoparticles Loaded with Farnesol or Geraniol to Enhance the Susceptibility of E. coli MCR-1 to Colistin

Pharmaceutics, 2021
Resistance to colistin, one of the antibiotics of last resort against multidrug-resistant Gram-negative bacteria, is increasingly reported. Notably, MCR plasmids discovered in 2015 have now been reported worldwide in humans.
Chantal Valcourt, Julien M. Buyck, Nicolas Grégoire, William Couet, Sandrine Marchand, Frédéric Tewes   +5 more
doaj   +1 more source

Comparison between Colistin Sulfate Dry Powder and Solution for Pulmonary Delivery

Pharmaceutics, 2020
To assess the difference in the fate of the antibiotic colistin (COLI) after its pulmonary delivery as a powder or a solution, we developed a COLI powder and evaluated the COLI pharmacokinetic properties in rats after pulmonary administration of the ...
Frédéric Tewes, Julien Brillault, Nicolas Gregoire, Jean-Christophe Olivier, Isabelle Lamarche, Christophe Adier, Anne-Marie Healy, Sandrine Marchand   +7 more
doaj   +1 more source

Anti-Infective Treatment and Resistance Is Rarely Problematic with Eye Infections

Antibiotics, 2022
The treatment of eye infections is very different than treating other body infections that require systemic anti-infectives. Endophthalmitis, keratitis, conjunctivitis, and other ocular infections are treated with direct injection and with topical drops ...
Regis P. Kowalski, Shannon V. Nayyar, Eric G. Romanowski, Vishal Jhanji   +3 more
doaj   +1 more source

Evolution and Biological Evaluation of Matrinic Derivatives with Amantadine Fragments As New Anti-Influenza Virus Agents

Molecules, 2019
A series of novel tricyclic matrinic derivatives with 11-adamantyl substitution were designed, synthesized, and evaluated for their activities against Influenza A H3N2 virus, based on the privileged structure strategy.
Tianyu Niu, Xiaoqiang Zhao, Jing Jiang, Haiyan Yan, Yinghong Li, Sheng Tang, Yuhuan Li, Danqing Song   +7 more
doaj   +1 more source