Results 21 to 30 of about 119,511 (340)

Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design. [PDF]

open access: yes, 2011
The relaxed complex scheme, a virtual-screening methodology that accounts for protein receptor flexibility, was used to identify a low-micromolar, non-bisphosphonate inhibitor of farnesyl diphosphate synthase.
Cao, Rong   +7 more
core   +2 more sources

Phytomedicinal properties of Hygrophila schulli (Neeramulliya) [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Hygrophila schulli which is known as “Neermulli’’ in the vernacular is an herbaceous plant native to Sri Lanka. Ancient medicinal literature suggests the use of H.
Malshani Nissanka   +5 more
doaj   +1 more source

Linking sustainable use policies to novel economic incentives to stimulate antibiotic research and development

open access: yesInfectious Disease Reports, 2017
There is now global recognition that antibiotic resistance is an emerging public health threat. Policy initiatives are underway to provide concrete suggestions for overcoming important obstacles in the fight against antibiotic resistance, like the ...
Ursula Theuretzbacher   +2 more
doaj   +1 more source

Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]

open access: yes, 2018
This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau   +3 more
core   +2 more sources

Factors associated with PPSV23 coverage among older adults in Japan: a nationwide community-based survey

open access: yesBMJ Open, 2019
Objectives The 23-valent pneumococcal polysaccharide vaccine (PPSV23) was included in Japan’s national immunisation programme for older adults in 2014.
Yoshitaka Murakami   +5 more
doaj   +1 more source

Broken drug markets in infectious diseases: Opportunities outside the private sector? [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2019
A subset of anti-infective drugs are increasingly unavailable for patients in the United States due to pricing or withdrawal from the market. Timely market solutions are needed.
Jonathan D Alpern   +2 more
doaj   +1 more source

Insights into early stage of antibiotic development in small- and medium-sized enterprises: a survey of targets, costs, and durations

open access: yesJournal of Pharmaceutical Policy and Practice, 2018
Background Antibiotic innovation has dwindled to dangerously low levels in the past 30 years. Since resistance continues to evolve, this innovation deficit can have perilous consequences on patients.
Christine Årdal   +6 more
doaj   +1 more source

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

open access: yes, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K   +11 more
core   +3 more sources

Liposomes used in the delivery of various antimicrobials to biofilm-producing infections: a systematic review [PDF]

open access: yesNanomedicine Journal
Objective(s): Persistent clinical infections have driven extensive research to find effective solutions. Liposomes, known for their biocompatibility, versatility, targetability, and tunability, have emerged as a prominent drug delivery system.
Manouchehr Teymouri   +7 more
doaj   +1 more source

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