Results 41 to 50 of about 119,511 (340)

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A, A, A, A, A, A, A, A, A, A, A, A, A, AA, AC, AH, AJ, AK, AK, AM, AW, B, B, B, B, BJ, C, C, C, C, CA, CA, CE, D, D, D, DG, DP, E, EA, EE, F, F, F, F, FA, FM, FM, G, G, G, G, G, G, G, GA, GP, H, H, H, H, HAS, HE, I, I, I, I, IJ, J, J, JA, JE, JF, JG, JJ, JJ, JL, JR, JR, JR, JV, K, K, K, K, KA, KC, KYY, L, LJ, M, M, M, M, M, M, M, M, M, M, M, M, M, MA, MA, MA, MA, MC, MG, MM, MN, MP, N, N, NT, O, OR, P, P, P, P, PF, PK, R, R, R, R, R, R, R, RB, RG, RM, RR, RR, RS, RV, S, S, S, S, S, S, S, S, S, Sartelli, SJ, SK, SK, SM, SR, SR, SY, T, T, TL, TM, V, V, VG, VN, W, W, W, WL, WR, Y, YF, YH, YR, YS, Z, ZJ   +173 more
core   +4 more sources

Teixobactin: a novel anti-infective agent [PDF]

Expert Review of Anti-infective Therapy, 2018
In 2015, a screen of bacterial strains produced a novel antibiotic with broad antimicrobial activity known as teixobactin [1].
openaire   +2 more sources

Thiourethane-functionalized fillers: biological properties and degradation resistance [PDF]

Brazilian Oral Research
This study determined the effect of thiourethane-functionalized fillers (TU) on the antimicrobial properties, cytotoxicity, degree of conversion (DC), water sorption (Wsp) and solubility (Wsl) of experimental composites. TU-modified fillers were added at
Larissa Maria CAVALCANTE, Amanda Barreto RAMOS, Daniela Costa SILVA, Gutemberg Gomes ALVES, Karinne Bueno ANTUNES, Carmem Silvia PFEIFER, Luis Felipe Jochims SCHNEIDER   +6 more
doaj   +2 more sources

Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]

, 2015
Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne, Ahmad, Amais, Christiansen, Lasse Engbo, Damborg, Peter, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +9 more
core   +4 more sources

Circumventing resistance to anti-infective agents [PDF]

Expert Opinion on Pharmacotherapy, 2015
The search for anti-infective agents to treat infections caused by a variety of pathogenic organisms has a long history.
openaire   +3 more sources

Synthesis and antimicrobial activity of 3,5-R-4-(3-(5-nitrofuran-2-yl)-allylidenamino)-1-R1-4H-1,2,4-triazole halides derivatives

Zaporožskij Medicinskij Žurnal, 2015
Aim. A number of new 3,5-R-4-(3-(5-nitrofuran-2-yl)allylidenami-no)-1-R1-4H-1,2,4-triazole halides have been synthesized, the structure of synthesized compounds has been proved by modern physical-chemical methods. Methods and results.
T. S. Brytanova , A. S. Gotsulya, O. I. Panasenko, Ye. G. Knysh, N. S. Fedyunina   +4 more
doaj   +1 more source

Maximum inhibitory dilution of mouthwashes containing chlorhexidine and polyhexamethylene biguanide against salivary staphylococcus aureus

Journal of Applied Oral Science, 2008
OBJECTIVE: The aim of the present study was to determine the in vitro maximum inhibitory dilution (MID) of two chlorhexidinebased oral mouthwashes (CHX): Noplak®, Periogard®, and one polyhexamethylene biguanide-based mouthwash (PHMB): Sanifill Premium ...
Andresa Piacezzi Nascimento, Juliane Maria Guerreiro Tanomaru, Fumio Matoba-Júnior, Evandro Watanabe, Mario Tanomaru-Filho, Izabel Yoko Ito   +5 more
doaj   +1 more source

Penetration of Anti-Infective Agents into Pulmonary Epithelial Lining Fluid [PDF]

Clinical Pharmacokinetics, 2011
Epithelial lining fluid (ELF) is often considered to be the site of extracellular pulmonary infections. During the past 25 years, a limited number of studies have evaluated the intrapulmonary penetration of antifungal, antitubercular, antiparasitic and antiviral agents. For antifungal agents, differences in drug concentrations in ELF or bronchoalveolar
Keith A. Rodvold, Jomy George, Liz Yoo
openalex   +3 more sources

A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]

, 2013
The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen, Geldhof, Peter, Masure, Dries, Van Den Broeck, Wim, Vercruysse, Jozef, Vlaminck, Johnny, Wang, Tao   +6 more
core   +4 more sources

‘Piloting a framework for analysing the public contributions to R&D: new antibiotics in focus’

Journal of Pharmaceutical Policy and Practice
Background Within the context of increasing transparency around public contributions, a framework for reporting and analysing public contributions to research and development (R&D) was previously developed and is piloted here using the example of ...
Louise Schmidt, Ozren Sehic, Ursula Theuretzbacher, Daniel Fabian, Claudia Wild   +4 more
doaj   +1 more source