Results 131 to 140 of about 1,249,360 (312)
Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration
Nano-Micro LettersAbstractInflammatory skin disorders can cause chronic scarring and functional impairments, posing a significant burden on patients and the healthcare system. Conventional therapies, such as corticosteroids and nonsteroidal anti-inflammatory drugs, are limited in efficacy and associated with adverse effects.
Amal George Kurian +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
npj Aging and Mechanisms of Disease, 2018 Aging and Inflammation: Targeting a cellular receptor reduces the deleterious inflammation during aging and anti-cancer therapy A sensing protein that is increased in response to DNA damage can be targeted to reduce inflammation and collateral damage ...
Raji R. Nair +2 more
doaj +1 more source
The Protective Role of Feruloylserotonin in LPS-Induced HaCaT Cells
Molecules, 2019 Epidermal inflammation is caused by various bacterial infectious diseases that impair the skin health. Feruloylserotonin (FS) belongs to the hydroxycinnamic acid amides of serotonin, which mainly exists in safflower seeds and has been proven to have anti-
Yuzhu He +8 more
doaj +1 more source
ANTI – INFLAMMATION PHAGE THERAPY:REVIVAL [PDF]
Современные проблемы науки и образования (Modern Problems of Science and Education), 2015 M.M. Padrul +3 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Optimizing combination of sambiloto herbal water fraction and salam leaf water fraction as anti-inflammation [PDF]
, 2015 Sambiloto herbs and salam leaves, which are effective to reduce blood sugar level with different mechanism, have been suggested to produce a synergy as antioxidant and anti-inflammatory agent, hence the optimum combination formula is remained to be ...
Mustafa, Raymond Harris +4 more
core
New nor-oleanane triterpenoids from the fruits of Stauntonia brachyanthera with potential anti-inflammation activity [PDF]
, 2019 The continuing studies on the fruits of Stauntonia brachyanthera led to the isolations of 6 normal and nor-oleanane triterpenoids, including two new compounds, brachyantheoraside B10 (1) and brachyantheraside C1 (2).
Dali Meng (5352140) +3 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Anti‐inflammation – just another word for anti‐ageing?
The Journal of Physiology, 2009 Sarcopenia, the Greek term for ‘poverty of flesh’, refers to age-associated loss of muscle mass and strength. The cost of ageing is a potential unmanageable burden for society and ageing-related diseases remain a major challenge to the national healthcare systems.
openaire +4 more sources