Results 41 to 50 of about 2,175,618 (339)
Frontiers in Molecular Neuroscience, 2019 The essential roles of microglia in maintaining homeostasis in the healthy brain and contributing to neuropathology are well documented. Emerging evidence suggests that epigenetic modulation regulates microglial behavior in both physiological and ...
Yawei Guo +7 more
doaj +1 more source
Long non-coding RNAs: Potential therapeutic targets for epilepsy
Frontiers in Neuroscience, 2022 Epilepsy is a common and disastrous neurological disorder characterized by abnormal firing of neurons in the brain, affecting about 70 million people worldwide.
Sen Liu +14 more
doaj +1 more source
The Pharmacological Potential of Mushrooms [PDF]
, 2005 This review describes pharmacologically active compounds from mushrooms. Compounds and complex substances with antimicrobial, antiviral, antitumor, antiallergic, immunomodulating, anti-inflammatory, antiatherogenic, hypoglycemic, hepatoprotective and ...
Jülich, Wolf-Dieter +2 more
core +3 more sources
Dendrimers as anti-inflammatory agents [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2013 Dendrimers constitute an intriguing class of macromolecules which find applications in a variety of areas including biology. These hyperbranched macromolecules with tailored backbone and surface groups have been extensively investigated as nanocarriers for gene and drug delivery, by molecular encapsulation or covalent conjugation.
Ashok K. Kakkar +3 more
openaire +4 more sources
Frontiers in Immunology, 2018 Fibroblast-like synoviocytes (FLS) and macrophage-like synoviocytes (MLS) are the two main cellular components of the synovium. It has been widely reported that FLS and MLS play essential roles in the joint pathology of rheumatoid arthritis (RA ...
Jiajie Tu +7 more
doaj +1 more source
The Role of CTHRC1 in Regulation of Multiple Signaling and Tumor Progression and Metastasis
Mediators of Inflammation, 2020 Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon-injured vessels and promotes cell migration and tissue ...
Dan Mei +3 more
doaj +1 more source
The application of HER2 and CD47 CAR-macrophage in ovarian cancer
Journal of Translational Medicine, 2023 Background The chimeric antigen receptor (CAR)-T therapy has a limited therapeutic effect on solid tumors owing to the limited CAR-T cell infiltration into solid tumors and the inactivation of CAR-T cells by the immunosuppressive tumor microenvironment ...
Yizhao Chen +17 more
doaj +1 more source
Journal of Ginseng Research, 2023 Background: As a complication of Type II Diabetes Mellitus (T2DM), the etiology, pathogenesis, and treatment of cognitive dysfunction are still undefined.
Xianan Dong +8 more
doaj +1 more source
The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels. [PDF]
, 2016 We tested the hypothesis that the anti-inflammatory actions of atrial natriuretic peptide (ANP) result from the modulation of leukocyte adhesion to inflamed endothelium and not solely ANP ligation of endothelial receptors to stabilize endothelial barrier
Adamson, Roger H +5 more
core +2 more sources
Metallothionein as an Anti-Inflammatory Mediator [PDF]
Mediators of Inflammation, 2009 The integration of knowledge concerning the regulation of MT, a highly conserved, low molecular weight, cystein-rich metalloprotein, on its proposed functions is necessary to clarify how MT affects cellular processes. MT expression is induced/enhanced in various tissues by a number of physiological mediators.
Masahiko Satoh +3 more
openaire +4 more sources