Results 171 to 180 of about 7,096,396 (300)

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Transcriptomic analysis reveals FcγR-mediated phagocytosis as a key pathway for the anti-inflammatory action of <i>Polygonatum sibiricum</i> polysaccharides in loach. [PDF]

Front Genet
Zhao Y, Xu X, Fan R, Dai L, Chen L.
europepmc   +1 more source

Preparation of Apoastaxanthinals and Evaluation of Their Anti-inflammatory Action against Lipopolysaccharide-Stimulated Macrophages and Adipocytes. [PDF]

ACS Omega, 2022
Takatani N, Beppu F, Yamano Y, Maoka T, Miyashita K, Hosokawa M.   +5 more
europepmc   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Context-dependent Activities of Mitrephorone Link Lipid Redirection, Anti-inflammatory Action, and Ferroptosis Control to Hepatocyte Protection. [PDF]

Theranostics
Waltl L, Wein LA, Bereuter L, Su F, Barta H, Xuan LL, Holubek D, Eshkaftaki ZM, Puskac K, Siller A, Schlenke P, Schennach H, Pferschy-Wenzig EM, Schött H, Racedo S, Koeberle SC, Magauer T, Koeberle A.   +17 more
europepmc   +1 more source

Synergistic antioxidant and anti-inflammatory action of N-acetylcysteine in portal hypertensive gastropathy in rats. [PDF]

Hepatol Forum, 2022
Licks F, Minuzzo Hartmann R, Schemitt E, Raskopf Colares J, Marques C, Fillmann H, Possa Marroni N.   +6 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Hybrids of Benzenesulfonamide Oxadiazole Derivatives with Dual CA II and COX-2 Inhibitory Activity Demonstrating Antiglaucoma and Anti-inflammatory Action: Synthesis, In Silico Insights, and In Vitro and In Vivo Bioevaluation. [PDF]

J Med Chem
Ezzat MAF, Seif EM, Nassar H, Bonardi A, Ferraroni M, Attia AA, Khater YTT, Rasheed RA, Abd El-Ghafar OAM, Allam HA, Angeli A, Schmidt M, Supuran CT, Ibrahim HS.   +13 more
europepmc   +1 more source

Libidibia ferrea (jucá) anti-inflammatory action: A systematic review of in vivo and in vitro studies. [PDF]

PLoS One, 2021
Almeida NCOS, Silva FRP, Carneiro ALB, Lima ES, Barcellos JFM, Furtado SC.   +5 more
europepmc   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source