In vivo antinociceptive and anti-inflammatory potential of hesperidin and its cyclodextrin inclusion compounds [PDF]
Introduction. This study aims to evaluate the antinociceptive activity on inflammatory and non-inflammatory nociception models, as well as the anti-inflammatory action of hesperidin and its inclusion compounds with beta-cyclodextrin and hydroxypropyl ...
CORCIOVĂ Andreia +5 more
doaj +1 more source
Anti-inflammatory effect of antiplasmin agents,ε -aminocaproic acid and trans-4-aminomethyl-cyclohexane carboxylic acid, in rats [PDF]
1. Both EACA and AMCHA clearly showed an anti-inflammatory effect, by intravenous, intramuscular, or oral route, against inflammatory edema produced in rats by intracutaneous injection of rabbit's anti-rat serum, carrageenin, histamine, serotonin, or ...
Kitamura, Mitsuyasu +2 more
core +1 more source
Polyelectrolyte multilayer assembly bearing ketoprofen for transdermal delivery [PDF]
A novel microencapsulation technology based on layer-by-layer assembly has been extensively studied and used for controlled delivery of drug microcrystal having poor aqueous solubility and low bioavailability.
Preeti Yadav +2 more
core +2 more sources
Preventive anti-inflammatory activity of an aqueous extract of larrea divaricata cav. and digestive and hematological toxicity [PDF]
Larrea divaricata Cav. commonly known as “jarilla hembra” is used in folklore medicine as anti-inflammatory. There was no scientific evidence justifying the medicinal use of the aqueous extract for inflammation diseases. Nowadays, there are two principal
Alonso, Rosario +4 more
core +1 more source
Structural modification of the antidepressant mianserin suggests that its anti-inflammatory activity may be independent of 5-Hydroxytryptamine receptors [PDF]
Antidepressants are increasingly recognized to have anti-inflammatory properties in addition to their ability to treat major depressive disorders. To explore if engagement of 5-hydroxytryptamine (5-HT) receptors was required for the anti-inflammatory ...
Chamberlain, Giselle +4 more
core +4 more sources
In Silico screening of nonsteroidal anti-inflammatory drugs and their combined action on Prostaglandin H Synthase-1 [PDF]
The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective ...
Demin, Oleg +5 more
core +5 more sources
Strong and Long-Lasting Antinociceptive and Anti-inflammatory Conjugate of Naturally Occurring Oleanolic Acid and Aspirin [PDF]
The conjugate 8 was obtained as a result of condensation of 3-hydroxyiminooleanolic acid morfolide (7) and aspirin in dioxane. Analgesic effect of OAO-ASA (8) for the range of doses 0.3 – 300.0 mg/kg (p.o.) was performed in mice using a hot plate test ...
Anna Bogacz +8 more
core +2 more sources
The Molecular Pharmacology of Phloretin: Anti-Inflammatory Mechanisms of Action
The isolation of phlorizin from the bark of an apple tree in 1835 led to a flurry of research on its inhibitory effect on glucose transporters in the intestine and kidney.
Solomon Habtemariam
doaj +1 more source
Graminex pollen: phenolic pattern, colorimetric analysis and protective effects in immortalized prostate cells (PC3) and rat prostate challenged with LPS [PDF]
Prostatitis, a general term describing prostate inflammation, is a common disease that could be sustained by bacterial or non-bacterial infectious agents.
Brunetti, Luigi +12 more
core +2 more sources
The methods to obtain chitooligosaccharides are tightly related to the physicochemical properties of the end products. Knowledge of these physicochemical characteristics is crucial to describing the biological functions of chitooligosaccharides ...
Ángela Sánchez +5 more
doaj +1 more source

