Results 61 to 70 of about 26,381,217 (279)

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

sj-docx-1-acr-10.1177_02841851221091443 - Supplemental material for Brain MRI features of anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis secondary to central nervous system infection in adult patients

open access: yes, 2022
Supplemental material, sj-docx-1-acr-10.1177_02841851221091443 for Brain MRI features of anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis secondary to central nervous system infection in adult patients by Sirong Piao, Yifang Bao, Liqin Yang ...
Yi Zhang (9093)   +7 more
core   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

Demyelinating disease and anti-N-methyl-D-aspartate receptor immunoglobulin G antibodies: a case report [PDF]

open access: yes, 2015
Background: Anti–N-methyl-D-aspartate receptor immunoglobulin G antibodies directed against the GluN1 subunit are considered highly specific for anti-N-methyl-D-aspartate receptor encephalitis, a severe clinical syndrome characterized by seizures ...
Schwab, Stefan   +6 more
core   +3 more sources

Table_1_Systematic review: clinical characteristics of anti-N-methyl-D-aspartate receptor encephalitis.DOCX

open access: yes, 2023
BackgroundThe number of reported cases of anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis has gradually increased since its discovery in 2007, while there are no uniform treatment guidelines.ObjectiveTo summarize the clinical characteristics
Jing Shi (16730)   +5 more
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Gut microbiome changes in anti-N-methyl-D-aspartate receptor encephalitis patients

open access: yesBMC Neurology, 2022
Background Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a type of autoimmune encephalitis. The underlying mechanism(s) remain largely unknown.
Jingya Wei   +8 more
doaj   +1 more source

Anti‑N-Methyl-D-Aspartate-Receptor Encephalitis in Young Females

open access: yesTurkish Journal of Anesthesia and Reanimation, 2018
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune-mediated disease commonly associated with ovarian teratoma. Anti-NMDA-receptor autoantibodies disrupt NMDA function leading to the development of psychosis, seizures and autonomic dysfunction. The treatment includes underlying tumour resection and immunosuppression.
Kamlesh, Kumari   +3 more
openaire   +2 more sources

Table_1_Clinical Characteristics of Anti-N-Methyl-d-Aspartate Receptor Encephalitis Overlapping with Demyelinating Diseases: A Review.doc

open access: yes, 2022
Anti-N-methyl-d-aspartate receptor encephalitis (NMDARe), a common autoimmune encephalitis, can be accompanied by demyelinating disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte ...
Jinmei Li (414884)   +5 more
core   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

open access: yesAdvanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa   +11 more
wiley   +1 more source

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