Results 121 to 130 of about 1,938,563 (139)

Defined O-acetylated Neu5Ac substrates reveal position-specific preferences of gut bacterial sialidases. [PDF]

Glycobiology
Podvalnyy N, Plan L, Gut S, Figueiredo-Campos P, Lai CA, Hennet T.   +5 more
europepmc   +1 more source

Preclinical Evaluation of a Near-Infrared Labelled Antibody Targeting the Tumour Associated Xenoantigen N-Glycolyl-Neuraminic Acid GM3 Ganglioside. [PDF]

Mol Imaging Biol
Barreto K, Bernhard W, Toledo D, Jett K, Casaco A, León K, Geyer CR.   +6 more
europepmc   +1 more source

Biosynthetic and genetic pathways related to sialic acid metabolism. [PDF]

J Biol Chem
Huang S, van de Ven EGP, Tee T, Lefeber DJ.   +3 more
europepmc   +1 more source

Species-specific N-glycan patterns in animal and human breast milk samples. [PDF]

Front Nutr
Ret D, Gentile SA, Rohrhofer J, Koidl L, Cozzi F, Untersmayr E.   +5 more
europepmc   +1 more source

Eosinophils in inflammatory bowel disease pathogenesis: an ROS-centric view. [PDF]

Front Allergy
Tomii T, Kano G.
europepmc   +1 more source

Inactivation of the CMAH gene and deficiency of Neu5Gc play a role in human brain evolution. [PDF]

Inflamm Regen
Liu Y, Li J, Liu Q.
europepmc   +1 more source

Genetically modified pigs with α1,3-galactosyltransferase knockout and beyond: a comprehensive review of xenotransplantation strategies. [PDF]

Front Immunol
Stelcer E, Wozniak A, Magner D, Zeyland J.   +3 more
europepmc   +1 more source

Elicited and pre‐existing anti‐Neu5Gc antibodies differentially affect human endothelial cells transcriptome [PDF]

Xenotransplantation, 2019
AbstractHumans cannot synthesize N‐glycolylneuraminic acid (Neu5Gc) but dietary Neu5Gc can be absorbed and deposited on endothelial cells (ECs) and diet‐induced anti‐Neu5Gc antibodies (Abs) develop early in human life. While the interaction of Neu5Gc and diet‐induced anti‐Neu5Gc Abs occurs in all normal individuals, endothelium activation by elicited ...
Beatrice Charreau, Cristina Costa, Jean-Paul Soulillou   +2 more
exaly   +6 more sources

Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease [PDF]

Glycobiology, 2008
Human heterophile antibodies that agglutinate animal erythrocytes are known to detect the nonhuman sialic acid N-glycolylneuraminic acid (Neu5Gc). This monosaccharide cannot by itself fill the binding site (paratope) of an antibody and can also be modified and presented in various linkages, on diverse underlying glycans.
Nissi Varki, Ajit Varki, Xi Chen
exaly   +4 more sources

Serum Neu5Gc biomarkers are elevated in primary cutaneous melanoma [PDF]

Biochemical and Biophysical Research Communications, 2023
Cutaneous melanoma is one of the most aggressive and deadly types of skin cancer and rates of disease are continuing to increase worldwide. Currently, no serum biomarkers exist for the early detection of cutaneous melanoma. Normal human cells cannot make
Christopher Day, James Paton, Michael P Jennings   +2 more
exaly   +2 more sources