Results 131 to 139 of about 1,938,563 (139)
Cancers, 2018 International audienceBecause of a mutation of the gene allowing the synthesis of the Neu5Gc form of neuraminidic acid, humans lack the Neu5Gc present in other mammals and develop anti-Neu5Gc.
Jean-Paul Soulillou +2 more
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A simple method for assessment of human anti-Neu5Gc antibodies applied to Kawasaki disease (P3263)
The Journal of Immunology, 2013Abstract N-Glycolylneuraminic acid (Neu5Gc) is a dietary immunogenic sugar that metabolically incorporates into diverse glycoconjugates in humans. Anti-Neu5Gc antibodies are detected in all human sera, play a role in several inflammation-mediated pathologies and are potential diagnostics of such diseases.
Vered Padler-Karavani +5 more
openaire +1 more source
2023
lo studio si propone di verificare la validità dell’ipotesi del ruolo della dieta XENOSIALICA nella malattia di Crohn. Questa ipotesi correla specifici comportamenti alimentari, con l'insorgenza/incidenza di malattia di Crohn In pratica, l’assunzione degli alimenti xenosialici, in associazione a specifici sbilanciamenti del microbiota intestinale, sono
Carnevali, Fiorella, Cottone, Mario
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lo studio si propone di verificare la validità dell’ipotesi del ruolo della dieta XENOSIALICA nella malattia di Crohn. Questa ipotesi correla specifici comportamenti alimentari, con l'insorgenza/incidenza di malattia di Crohn In pratica, l’assunzione degli alimenti xenosialici, in associazione a specifici sbilanciamenti del microbiota intestinale, sono
Carnevali, Fiorella, Cottone, Mario
openaire +2 more sources
Blood, 2004
Abstract Humans are incapable of synthesizing the common mammalian cell surface sialic acid N-glycolylneuraminic acid (Neu5Gc), due to an irreversible genetic mutation that occurred after our last common ancestor with great apes. Despite this, we found trace levels of Neu5Gc in certain normal human tissues, and higher levels in fetal and
Dzung H. Nguyen +2 more
openaire +1 more source
Abstract Humans are incapable of synthesizing the common mammalian cell surface sialic acid N-glycolylneuraminic acid (Neu5Gc), due to an irreversible genetic mutation that occurred after our last common ancestor with great apes. Despite this, we found trace levels of Neu5Gc in certain normal human tissues, and higher levels in fetal and
Dzung H. Nguyen +2 more
openaire +1 more source
Influence des anticorps anti-Neu5Gc et anti-alpha-1-3-Galactose dans la réponse immunitaire
L’espèce humaine a perdu lors de l’évolution la capacité de synthétiser certains hydrates de carbone et voit sa glycosylation des protéines et des lipides modifiée par rapport aux autres mammifères. Certains motifs glycosylés acquis lors de l’ingestion de denrées d’origine animale ou produits par le microbiote intestinal peuvent être incorporés dans ...openaire +1 more source
Potential deleterious role of anti‐Neu5Gc antibodies in xenotransplantation
Xenotransplantation, 2015Jean-Paul Soulillou +2 more
exaly
Characterization of immunogenic Neu5Gc in bioprosthetic heart valves
Xenotransplantation, 2016Cristina Costa +2 more
exaly