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Frontiers in Nutrition, 2021 Sialic acids are postulated to improve cognitive abilities. This study aimed to evaluate the effects of sialic acid on behavior when administered in a free form as N-acetylneuraminic acid (Neu5Ac) to pregnant mothers or rat pups.
Dongsheng Bian
exaly +3 more sources
Foods, 2023 Sialic acids (Sias) are acidic monosaccharides and red meat is a notable dietary source of Sia for humans. Among the Sias, N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) play multiple roles in immunity ...
Peter Wynn, Marefa Jahan, Bing Wang
exaly +3 more sources
Correlation of Serum N-Acetylneuraminic Acid with the Risk of Moyamoya Disease
Brain Sciences, 2023 N-acetylneuraminic acid (Neu5Ac) is a functional metabolite and has been demonstrated to be a risk factor for cardiovascular diseases. It is not clear whether Neu5Ac is associated with a higher risk of cerebrovascular disorders, especially moyamoya ...
Chenglong Liu +15 more
doaj +1 more source
Recent advances on N-acetylneuraminic acid: Physiological roles, applications, and biosynthesis
Synthetic and Systems Biotechnology, 2023 N-Acetylneuraminic acid (Neu5Ac), the most common type of Sia, generally acts as the terminal sugar in cell surface glycans, glycoconjugates, oligosaccharides, lipo-oligosaccharides, and polysaccharides, thus exerting numerous physiological functions ...
Mingli Zhao +4 more
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Metabolites, 2023 The healthy growth of infants during early life is associated with lifelong consequences. Breastfeeding has positive impacts on reducing obesity risk, which is likely due to the varied components of breast milk, such as N-acetylneuraminic acid (Neu5Ac ...
Runze Ouyang +14 more
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Biological functions of sialic acid as a component of bacterial endotoxin
Frontiers in Microbiology, 2022 Lipopolysaccharide (endotoxin, LPS) is an important Gram-negative bacteria antigen. LPS of some bacteria contains sialic acid (Neu5Ac) as a component of O-antigen (O-Ag), in this review we present an overview of bacteria in which the presence of Neu5Ac ...
Bartłomiej Dudek +6 more
doaj +1 more source
Shift of the reaction equilibrium at high pressure in the continuous synthesis of neuraminic acid
Beilstein Journal of Organic Chemistry, 2022 The importance of a compound that helps fight against influenza is, in times of a pandemic, self-evident. In order to produce these compounds in vast quantities, many researchers consider continuous flow reactors in chemical industry as next stepping ...
Jannis A. Reich +5 more
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Comparison of sialic acid content in bovine and buffalo milk and meat
Revista Científica, 2023 Animal-origin food, such as meat and milk, are important sources of sialic acids (SIAs) with relevant implications for human health. Two significant SIAs in mammals are N-acetyl-neuraminic acid (Neu5Ac) and N- glycolylneuraminic acid (Neu-5Gc).
Michela Contò +2 more
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BMC Cardiovascular Disorders, 2020 Background N-acetylneuraminic acid (Neu5Ac) is a functional metabolite involved in coronary artery disease (CAD). We aimed to evaluate the relationship between serum Neu5Ac and the risk and prognosis of acute coronary syndrome (ACS) in a real-world ...
Miao-Nan Li +11 more
doaj +1 more source
Serum N-Acetylneuraminic Acid Is Associated with Atrial Fibrillation and Left Atrial Enlargement
Cardiology Research and Practice, 2020 Purpose. Recent studies have indicated that N-acetylneuraminic acid (Neu5Ac) plays a key role in severe coronary artery diseases, involving RhoA signaling pathway activation, which is critically involved in cardiac fibrosis.
Wei Hu +11 more
doaj +1 more source