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A study of an anti-obesity, anti-obesity campaign
2021Since the declaration of the “war on obesity,” there have been many attempts to curb the so-called “obesity epidemic.” Indeed, anti-obesity campaigns communicating a “fat-as-fatal” message have become a regular and accepted public health strategy in most economically developed countries.
Lee, Jessica, Williams, Benjamin
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Current Opinion in Lipidology, 2015
The prevalence of obesity across the world continues to climb, bringing with it otherwise preventable obesity-related comorbidities including type 2 diabetes, hypertension and cardiovascular disease. Weight loss is difficult to achieve and maintain through lifestyle interventions alone, leading to intense efforts to develop adjunctive pharmacological ...
Rankin, W., Wittert, G.
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The prevalence of obesity across the world continues to climb, bringing with it otherwise preventable obesity-related comorbidities including type 2 diabetes, hypertension and cardiovascular disease. Weight loss is difficult to achieve and maintain through lifestyle interventions alone, leading to intense efforts to develop adjunctive pharmacological ...
Rankin, W., Wittert, G.
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Expert Opinion on Pharmacotherapy, 2008
Recent discoveries about the metabolic and genetic control systems that govern regulation of body weight and energy expenditure have afforded the opportunity to develop pharmacological agents that can be used as adjunctive treatments for patients with obesity. However, the scarcity of medications available or those that have made it to Phase III trials
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Recent discoveries about the metabolic and genetic control systems that govern regulation of body weight and energy expenditure have afforded the opportunity to develop pharmacological agents that can be used as adjunctive treatments for patients with obesity. However, the scarcity of medications available or those that have made it to Phase III trials
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An anti-obesity immunotherapy?
Science, 2021Adipose tissue–resident macrophages promote lipid storage in mice but can be stopped with antibody ...
O'Brien, Conan J. O., Domingos, Ana I.
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Expert Opinion on Investigational Drugs, 2002
Obesity accelerates morbidity and mortality and has been described by the World Health Organization (WHO) as an epidemic in many industrialised nations [101,102]. Diet, exercise and lifestyle recommendations have proven to be mostly ineffective in adequately preventing or treating the progression of this public health disease.
Harold, Bays, Carlos, Dujovne
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Obesity accelerates morbidity and mortality and has been described by the World Health Organization (WHO) as an epidemic in many industrialised nations [101,102]. Diet, exercise and lifestyle recommendations have proven to be mostly ineffective in adequately preventing or treating the progression of this public health disease.
Harold, Bays, Carlos, Dujovne
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Expert Opinion on Investigational Drugs, 2000
There is increasing evidence that body weight is homeostatically regulated and that in obesity this regulation maintains weight at a high level. Weight loss activates mechanisms that are designed to return individuals to their pre-existing weight. This explains the universally poor results of current strategies to maintain weight loss.
J, Proietto +3 more
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There is increasing evidence that body weight is homeostatically regulated and that in obesity this regulation maintains weight at a high level. Weight loss activates mechanisms that are designed to return individuals to their pre-existing weight. This explains the universally poor results of current strategies to maintain weight loss.
J, Proietto +3 more
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Advances in anti-obesity therapeutics
Expert Opinion on Investigational Drugs, 2005Obesity is rapidly becoming an epidemic in developed countries. Currently available anti-obesity therapeutics are only modestly effective and are accompanied by significant adverse effects. In recent years, substantial advances have been made in the basic understanding of brain control of feeding behaviour and metabolism. As a result, several compounds
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Prescribing anti-obesity preparations
Nurse Prescribing, 2010After a brief consideration of body mass index as a measure of obesity and the types of pharmacological interventions available, the article focuses on orlistat, the only licensed anti-obesity drug described in the British National Formulary. A consideration of the mechanism of action of this agent and a discussion of specific prescribing issues are ...
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Food Ingredients as Anti-Obesity Agents
Trends in Endocrinology & Metabolism, 2015Brown adipose tissue (BAT) is a site of adaptive non-shivering thermogenesis after cold exposure, and is involved in the regulation of energy expenditure and body fatness. BAT can be activated and recruited by not only cold exposure but also by various food ingredients including capsaicin in chili pepper and catechins in green tea, which would be ...
Masayuki, Saito +2 more
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Capsaicin as an Anti-Obesity Drug
2014Laboratory studies support a role of capsaicin as an anti-obesity agent. Intestinal mucosal afferent nerves appear to play a role in controlling adipose tissue distribution between visceral and subcutaneous sites. Activation of the transient receptor potential vanilloid-1 channels by capsaicin prevents adipogenesis. A neurogenic mechanism modulates the
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