Results 241 to 250 of about 2,119,412 (309)

Reducing Exposure Before Birth: An Interrupted Time Series Study of Prenatal Exposure to Fetotoxic Medications Under Risk Management Plans in Canada

Clinical Pharmacology &Therapeutics, EarlyView.
Canada's 2009 risk management plan (RMP) framework has not been evaluated for prenatal exposure impact. Conversely, widely used drugs such as nonsteroidal anti‐inflammatory drugs (NSAIDs) lack RMPs. We assessed first‐trimester exposure to RMP‐regulated medications following regulatory interventions and to NSAIDs following safety publications.
Nahiyan Saiyara Khan, Odile Sheehy, Lisiane Freitas Leal, Vanina Tchuente, Anick Bérard   +4 more
wiley   +1 more source

Anti-Obesity Effects of LB-GABA. [PDF]

Int J Mol Sci
Han H, Song G, Kim J, Jin H, Lee BY.
europepmc   +1 more source

Prescription Sequence Symmetry Analysis of Glucagon‐Like Peptide‐1 Receptor Agonists and Neuropsychiatric Conditions

Clinical Pharmacology &Therapeutics, EarlyView.
Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are increasingly prescribed for type 2 diabetes and weight management. However, conflicting evidence from preclinical, clinical, and pharmacovigilance studies suggests potential neuropsychiatric effects.
Maria J. Alfonso Arvez, Sam Wade, Darshna Goordeen, Jenni Ilomäki, Amanda J. Cross, Monica Langiu, George S. Q. Tan   +6 more
wiley   +1 more source

The effect of combining surgical or endoscopic bariatric interventions with anti-obesity medication or probiotics on weight loss: a narrative review. [PDF]

Front Endocrinol (Lausanne)
de Waal JR, Nieuwdorp M, Gerdes VEA.
europepmc   +1 more source

Investigations Into the Metabolism and Elimination of Tesofensine in Human Urine

Drug Testing and Analysis, EarlyView.
This study investigated tesofensine metabolism and urinary elimination after a single 483 μg intake via a dietary supplement. In six volunteers, urine was collected up to 659 h. LC‐HRMS/MS identified four tentative metabolites; maximum urinary concentrations reached 4 ng/mL within 4–48 h.
O. Krug, A. Thomas, M. Thevis
wiley   +1 more source

Expression of concern - Safety and effects of anti-obesity medications on weight loss, cardiometabolic, and psychological outcomes in people living with overweight or obesity: a systematic review and meta-analysis. [PDF]

EClinicalMedicine
The Editors For eClinicalMedicine.
europepmc   +1 more source

Benchmarking Generative Artificial Intelligence Against Human Judgment in Eating Disorder Case Recognition and Treatment Recommendations

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Generative AI is now used to access eating disorder (ED) information, yet the suitability of its outputs remains unclear. Using two vignettes, we evaluated generative AI's ability to accurately identify ED presentations and recommend appropriate care, while benchmarking its performance against published responses from human samples ...
Jake Linardon, Mariel Messer
wiley   +1 more source

Gastrointestinal Adverse Effects of Anti-Obesity Medications in Non-Diabetic Adults: A Systematic Review. [PDF]

Medicina (Kaunas)
Takrori E, Peshin S, Singal S.
europepmc   +1 more source

Associations Between Self and Peer's Fear of Fat in Predicting Dietary Restraint, Weight/Shape/Eating Concerns, and Thin‐Ideal Internalization: A Dyadic Exploration in Female Friend Pairs

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Fear of fat may reflect concern regarding rejection one may experience at a higher weight. Peers play a major role in socialization and support during adolescence and young adulthood. While studies have highlighted peers as an important source of influence underlying disordered eating, it is unclear whether one's own fear of fat or ...
Shannon M. O'Connor, Caroline G. Martin, Leora L. Haller, Shannon Marhan   +3 more
wiley   +1 more source

Mechanisms behind the anti-diabetic and anti-obesity effects of seaweeds or macroalgae and their bioactive compounds. [PDF]

World J Diabetes
Magwaza SN, Islam MS.
europepmc   +1 more source