Results 31 to 40 of about 2,742,410 (287)

Elucidating the anti-obesity phytochemicals in Chenpi and their molecular mechanisms

Food Science and Human Wellness
Obesity has become a signifi cant global public health issue. Previous studies have found that the Chenpi has the anti-obesity activity. However, the anti-obesity phytochemicals and their mechanisms are still unclear.
Jinhai Luo, Weiqi Yan, Zhi Chen, Baojun Xu   +3 more
doaj   +1 more source

Criteria for EASO-collaborating centres for obesity management

, 2011
Obesity is recognised as a global epidemic and the most prevalent metabolic disease world-wide. Specialised obesity services, however, are not widely available in Europe, and obesity care can vary enormously across European regions.
Hermann Toplak, Tsigos, C., Volkan Yumuk, Yves Schutz, Yumuk, V., Schutz, Yves, Roman, Gabriela, Tsigos, Constantine, Dragan Micic, Maximo Maislos, Basdevant, A., Yumuk, Volkan, Nick Finer, Constantine Tsigos, Mathus-Vliegen, E., Schutz, Y., Barbara Zahorska-Markiewicz, Basdevant, Arnaud, Finer, N., Yumuk, Volkan Demirhan, Hainer, V., Finer, Nick, Roman, G., Arnaud Basdevant, Maislos, M., Micic, Dragan, Toplak, Hermann, Micic, D., Toplak, H., Gabriela Roman, Zahorska-Markiewicz, B., Mathus-Vliegen, Elisabeth, Zahorska-Markiewicz, Barbara, Elisabeth Mathus-Vliegen, Vojtech Hainer, Maislos, Maximo, Hainer, Vojtech   +36 more
core   +1 more source

Research Progress on Anti Obesity Effects of Tea Polyphenols

Shipin gongye ke-ji
Obesity is a major risk factor and pathological basis for several chronic diseases such as diabetes, cardiovascular diseases, and tumors. It has now become a global public health issue.
Fei WANG, Shuxun YAN, Ping WANG
doaj   +1 more source

Adolescent experiences of anti‐obesity drugs [PDF]

Clinical Obesity, 2015
SummaryOnly two anti‐obesity drugs (AODs) are frequently prescribed in paediatric obesity, orlistat and metformin. Meta‐analyses show modest benefit in clinical trials, yet analyses of prescribing databases show high levels of discontinuation in routine clinical practice.
White, Billy, Jamieson, L, Clifford, S, Hamilton-Shield, Julian P, Christie, D, Smith, F, Wong, Ian C. K., Viner, R M   +7 more
openaire   +4 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Anti-obesity mechanisms elucidation of essential oil components from Artemisiae Argyi Folium (Aiye) by the integration of GC-MS, network pharmacology, and molecular docking

International Journal of Food Properties
Recently, the global epidemic of obesity is increasing significantly. Obesity is treated with anti-obesity medications and surgery and complications related to these treatments prompt the search of phytochemicals that confer anti-obesity effects ...
Yongxiang Liu, Jinhai Luo, Maninder Meenu, Baojun Xu   +3 more
doaj   +1 more source

Anti-obesity effect of extract from fermented Curcuma longa L. through regulation of adipogenesis and lipolysis pathway in high-fat diet-induced obese rats

Food & Nutrition Research, 2016
Background: Even though Curcuma longa L. possesses various biological activities, it has strong flavor and taste, which decrease consumer palatability and limit industrial applications in food.
Ji Hye Kim, Ok-Kyung Kim, Ho-Geun Yoon, Jeongjin Park, Yanghee You, Kyungmi Kim, Yoo-Hyun Lee, Kyung-Chul Choi, Jeongmin Lee, Woojin Jun   +9 more
doaj   +1 more source

Dipterocarpus tuberculatus as a promising anti-obesity treatment in Lep knockout mice

Frontiers in Endocrinology, 2023
IntroductionThe therapeutic effects and mechanisms of Dipterocarpus tuberculatus (D. tuberculatus) extracts have been examined concerning inflammation, photoaging, and gastritis; however, their effect on obesity is still being investigated.MethodsWe ...
Yu Jeong Roh, Su Jin Lee, Ji Eun Kim, You Jeong Jin, Ayun Seol, Hee Jin Song, Jumin Park, So Hae Park, Bounleuane Douangdeuane, Onevilay Souliya, Sun Il Choi, Dae Youn Hwang, Dae Youn Hwang   +12 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Revealing Molecular Mechanisms of the Bioactive Saponins from Edible Root of Platycodon grandiflorum in Combating Obesity

Plants
Obesity has emerged as a significant health concern, as it is a disease linked to metabolic disorders in the body and is characterized by the excessive accumulation of lipids.
Bincheng Han, Jinhai Luo, Baojun Xu
doaj   +1 more source