Results 41 to 50 of about 2,742,410 (287)

Metabolome and transcriptome signatures shed light on the anti-obesity effect of Polygonatum sibiricum

open access: yesFrontiers in Plant Science, 2023
Obesity has become one of the major threats to human health across the globe. The rhizomes of Polygonatum sibiricum have shown promising anti-obesity effect. However, the metabolic and genetic basis mediating this beneficial effect are not fully resolved.
Xiaobin Ou   +9 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Guidelines for anti‐obesity assays in Drosophila melanogaster model

open access: yesFuture Postharvest and Food
Accumulating evidence showed that obesity leads to severe and various diseases chronically. Although the long list of mechanisms that obesity can harm us is still elongating, more rapid animal models are desired to investigate and illustrate obesity and ...
Wanning Ma, Hui Cao
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Mechanisms of Body Weight Reduction by Black Tea Polyphenols

open access: yesMolecules, 2016
Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity.
Haibo Pan, Ying Gao, Youying Tu
doaj   +1 more source

Radical Scavenging-Linked Anti-Adipogenic Activity of Aster scaber Ethanolic Extract and Its Bioactive Compound

open access: yesAntioxidants, 2020
Aster scaber is a wild vegetable cultivated in Korea and is known to contain phytochemicals with various biological activities. The potential antioxidant and anti-obesity effects of A. scaber and their mechanism are yet to be reported.
Ye-Eun Choi   +8 more
doaj   +1 more source

Pancreatic Lipase Inhibition Activity in Lipid Absorption Using Traditional Plants: A Systematic Review and Meta-Analysis

open access: yesIndonesian Journal of Chemistry, 2023
Obesity is a complex and multifactorial disease resulting from excessive accumulation of fat. With a significant annual increase, it has become a health concern across the globe in the last decades.
Hasim Hasim   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Effects of Resveratrol on Adipocytes: Evidence from In Vitro and In Vivo Studies

open access: yesMolecules
Obesity, a prevalent global health issue, arises from an imbalance between caloric intake and energy expenditure, leading to the expansion of adipose tissue and metabolic dysfunction.
Matthew Terzo   +2 more
doaj   +1 more source

Anti-obesity drug delivery systems: recent progress and challenges

open access: yes, 2023
Obesity has reached an epidemic proportion in the last thirty years, and it is recognized as a major health issue in modern society now with the possibility of serious social and economic consequences.
Diganta Das (1254000)   +5 more
core   +5 more sources

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