Results 71 to 80 of about 3,380,027 (220)

Advancing In Vivo Chimeric Antigen Receptor T‐Cell Engineering to Accelerate Clinical Translation

MedComm, Volume 7, Issue 10, October 2026.
In vivo CAR‐T cell generation directly engineers endogenous T cells using pre‐manufactured gene delivery vectors that target T cells and deliver CAR‐encoding genetic material. The resulting CAR‐T cells expand in vivo and mediate antigen‐specific cytotoxicity.
Zhenxin Bai, Ming Yi, Shengtao Hu, Dixuan Xue, Luxin Wei, Lifeng Zhang, Zhijun Dai   +6 more
wiley   +1 more source

Evaluation of Adverse Drug Events in Patients on Anti-Retroviral Therapy Regimen at Omdurman Voluntary Counselling and Testing and Anti-Retroviral Therapy Center in Sudan – A Cross-Sectional Study [PDF]

Eiman Eltayeb M Ibrahim,1 Safaa Badi,1 Bashir A Yousef,2 LutzBashir A Elsayed,3 Habab K Elkheir1,4 1Department of Clinical Pharmacy, Faculty of Pharmacy, Omdurman Islamic University, Khartoum, Sudan; 2Department of Pharmacology, Faculty of Pharmacy ...
Badi S, Ibrahim EEM, Elsayed LA, Yousef BA, Elkheir HK   +4 more
core  

Development of retroviral vectors for selective gene transfer into haematopoietic precursor cells and investigation of the gamma-retroviral R-peptide mediated membrane fusion [PDF]

, 2009
Eine in vivo Modifizierung von Blutstammzellen wäre für eine Reihe gentherapeutischer Therapieansätze vorteilhaft. Dies würde voraussetzen, dass retrovirale Vektoren gezielt auf Blutstammzellen ausgerichtet werden können.
Bobkova, Maria
core  

Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole-Based Anticancer Agents as Potent Angiogenesis Inhibitors

, 2021
Background: Thiadiazole has attracted a great deal of interest as a versatile heterocycle for the discovery and development of potent anticancer agents. Thiadiazole derivatives exert potent antitumor activity against a variety of human cancer cell lines ...
Turan, Gulhan, Gülhan Turan, KAPLANCIKLI, ZAFER ASIM, ALTUĞ, BURCUGÜL, Ali S. Koparal, KOPARAL, ALİ SAVAŞ, Ayşe T. Koparal, Burcugül Altuğ-Tasa, Betül Kaya-Çavuşoğlu, Zafer A. Kaplancıklı, Kaya-cavusoglu, Betul   +10 more
core   +1 more source

Lipodistrofi akibat Anti Retroviral [PDF]

, 2010
HIV dan AIDS telah menjadi pandemi. Lebih dari 30 juta orang terinfeksi HIV terutama di daerah Afrika-Sahara. Penyakit ini dahulu memiliki tingkat kematian tinggi, namun semenjak digunakannya Highly Active Anti Retroviral Therapy (HAART), mortalitas ...
Simatupang, Abraham
core   +1 more source

Human immunodeficiency virus infection and autoimmune hepatitis during highly active anti-retroviral treatment: a case report and review of the literature

Journal of Medical Case Reports, 2011
Introduction The emergence of hepatic injury in patients with human immunodeficiency virus infection during highly active therapy presents a diagnostic dilemma. It may represent treatment side effects or autoimmune disorders, such as autoimmune hepatitis,
Higgins Martha, Kamran Farah, Nasser Haitham, Khatib Riad, Daas Hanady, Saravolatz Louis   +5 more
doaj   +1 more source

Semaglutide improves MASLD and MASH in people with HIV: The SLIM LIVER study

HIV Medicine, Volume 27, Issue 10, Page 1710-1714, October 2026.
Abstract Objectives We have shown that semaglutide, a glucagon‐like peptide‐1 receptor agonist (GLP‐1RA), is a highly effective therapy for metabolic dysfunction‐associated steatotic liver disease (MASLD) in people with HIV (PWH). The OWLiver® metabolomics algorithms allow non‐invasive MASLD severity staging without liver biopsy, but the use of ...
Jordan E. Lake, Douglas W. Kitch, Amy Kantor, Rebeca Mayo, Pablo Belaunzaran‐Zamudio, Carl J. Fichtenbaum, Todd T. Brown, Kathleen E. Corey, Fred Sattler, Kristine M. Erlandson   +9 more
wiley   +1 more source

Out-of-pocket Expenditure and its Impact on the Quality of Life among Patients Attending the Anti-retroviral Therapy Centre of a Tertiary Care Hospital in Kolkata [PDF]

Healthline
Introduction: Out-of-pocket expenditure (OOPE) has a negative impact on Quality of life (QoL) of People Living with HIV (PLHIV)which can increase the risk of slipping into poverty. Objectives: Primary Objective of this study was to estimate the burden of
Mamunur Rashid, Dipendra Narayan Goswami, Kuntala Ray, Mausumi Basu, Aparajita Mondal, Abhipsa Dey   +5 more
doaj   +1 more source

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar, Purbasa Dasgupta, Soma Ray, Soumen Paul   +3 more
wiley   +1 more source

Anti-HIV therapy: pipeline approaches and future directions [PDF]

, 2011
Human immunodeficiency virus (HIV), with about 30 million deaths and double infections (in developing countries), is an open challenge today for global scientists.
Lavkush Dwivedi, Mansi Shrivastava
core   +1 more source