Results 41 to 50 of about 49,611 (279)
A Practical Guide to the Treatment of Dravet Syndrome with Anti-Seizure Medication [PDF]
CNS Drugs, 2022 Dravet syndrome is a severe developmental and epileptic encephalopathy characterised by refractory seizures and cognitive dysfunction. The treatment is challenging, not least because the seizures are highly drug resistant, requiring multiple anti-seizure medications (ASMs), while some ASMs can exacerbate seizures.
Adam Strzelczyk, Susanne Schubert-Bast
openaire +3 more sources
Frontiers in Neurology, 2021 Purpose: To evaluate the efficacy and tolerability of adjunctive perampanel (PER) in Chinese patients with focal-onset seizures, with or without secondarily generalized tonic-clonic seizures.Methods: Fifty-six patients aged 14–72 years were recruited ...
Ranran Zhang +8 more
doaj +1 more source
Experimental Therapeutic Strategies in Epilepsies Using Anti-Seizure Medications
Journal of Experimental Pharmacology, 2021 Epilepsies are among the most common neurological problems. The disease burden in patients with epilepsy is significantly high, and epilepsy has a huge negative impact on patients' quality of life with epilepsy and their families. Anti-seizure medications are the mainstay treatment in patients with epilepsy, and around 70% of patients will ultimately ...
Fakher Rahim +3 more
openaire +6 more sources
Archives of Public Health, 2020 Background Epilepsy is the common neurological disorder in the world, affecting approximately 50 million people. Anti-epileptic medication non-adherence can be a reason for long term hospitalization, repeated emergency seizure attacks, increased health ...
Zelalem Belayneh, Birhanie Mekuriaw
doaj +1 more source
Safety and efficacy of rapid withdrawal of anti-seizure medication during long-term video-EEG monitoring. [PDF]
Front Neurol, 2023 ObjectiveAnti-seizure medications (ASMs) are often withdrawn during long-term video-EEG monitoring (LTM) to allow pre-surgical evaluation. Herein, we evaluated the safety and efficacy of ultra-rapid withdrawal (URW) and rapid withdrawal (RW) of ASMs in ...
Liu J, Chen D, Xu Y, Zhang Y, Liu L.
europepmc +2 more sources
Epilepsia Open, 2023 Objective Self‐limited infantile epilepsy (SeLIE) has distinctive clinical features, and the PRRT2 gene is known to be a considerable genetic cause.
Jiwon Lee +3 more
doaj +1 more source
Medication safety in children [PDF]
, 2015 Background: The issue of medication safety has received considerable attention in the last few years. Especially drug related problems (DRP) are a major safety issue.
Glanzmann, C, Glanzmann, Corina
core +1 more source
Brain and Behavior, 2023 Background Effective treatment of epilepsy is a major challenge in the field of neurology. Studies have suggested that melatonin can work in epilepsy with a good safety profile.
Mehdi Maghbooli +3 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2021 Background Tuberous sclerosis complex (TSC), a multisystem genetic disorder, affects many organs and systems, characterized by benign growths. This German multicenter study estimated the disease-specific costs and cost-driving factors associated with ...
Janina Grau +35 more
doaj +1 more source
Frontiers in Neurology, 2023 IntroductionFor drug resistant epilepsy patients who are either not candidates for resective surgery or have already failed resective surgery, neuromodulation is a promising option.
Madeline C. Fields +17 more
doaj +1 more source