Results 61 to 70 of about 49,611 (279)

Seizure control and its associated factors among epileptic patients at Neurology Clinic, University of Gondar hospital, Northwest Ethiopia

SAGE Open Medicine, 2022
Background: Epilepsy is characterized by two or more unprovoked recurrent seizures, which often respond to available antiseizure medications. However, seizure control among epileptic patients in the developing world is low.
Dawit Zena, Abilo Tadesse, Nebiyu Bekele, Samson Yaregal, Nuria Sualih, Edilawit Worku   +5 more
doaj   +1 more source

Novel subscalp and intracranial devices to wirelessly record and analyze continuous EEG in unsedated, behaving dogs in their natural environments: A new paradigm in canine epilepsy research

Frontiers in Veterinary Science, 2022
Epilepsy is characterized by unprovoked, recurrent seizures and is a common neurologic disorder in dogs and humans. Roughly 1/3 of canines and humans with epilepsy prove to be drug-resistant and continue to have sporadic seizures despite taking daily ...
Wolfgang Löscher, Wolfgang Löscher, Gregory A. Worrell, Gregory A. Worrell   +3 more
doaj   +1 more source

Anti‐seizure medications and risk of suicide: Re‐addressing the issue

International Journal of Clinical Practice, 2021
Although suicidal behaviour in epilepsy is a complex phenomenon, evidence suggests that suicide rates are higher amongst individuals with epilepsy than the general population. Yet, it has been a decade since the Food and Drug Administration (FDA) has passed a warning with anti-seizure medications (ASMs) and risk of suicide, the scientific community is ...
Sai Krishna Gudi, Qaiser Jahan
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Topographic distribution of seizure patterns in patients with absence epilepsy [PDF]

, 2010
Background: Absence seizures, which are also known as petit mal seizures, are the most common type of seizures in pediatric epilepsy. They appear in several types of epilepsy and are characterized by impaired consciousness and 3-Hz spike-and-slow-wave ...
Mazzaretto, Andrea
core  

Seizure cluster: Definition, prevalence, consequences, and management

, 2019
•Seizure clusters are common in patients with refractory epilepsy.•There is no agreed upon definition for seizure clusters.•Rescue medications are underutilized in seizure clusters.•Non-rectal, non-IV benzodiazepines are safe and effective in the ...
Saba Jafarpour, Kellinghaus, Christoph, Hirsch, Lawrence J, Marina Gaínza-Lein, Lawrence J. Hirsch, Jafarpour, Saba, Gaínza-Lein, Marina, Christoph Kellinghaus, Detyniecki, Kamil, Kamil Detyniecki   +9 more
core   +1 more source

Table1_Genotyping for HLA risk alleles versus patch tests to diagnose anti-seizure medication induced cutaneous adverse drug reactions.XLSX

, 2022
Aim: To provide a comparison of genotyping for HLA risk alleles versus patch testing to determine which of these two tests is a better diagnostic tool for cutaneous hypersensitivity reactions caused by anti-seizure medication.Methods: A literature study ...
Lisanne E. N. Manson (9408827), Patricia C. Y. Chan (14145342), Henk-Jan Guchelaar (78210), Stefan Böhringer (174739)   +3 more
core   +1 more source

Evaluation of two anti-seizure medication strategies in refractory epilepsy patients from a tertiary center with complementary insights from data visualization [PDF]

, 2021
Objective: To evaluate the healthcare resources in a tertiary center related to exclusive use of non-enzyme inducing anti-seizure medications relative to concomitant use of enzyme-inducing anti-seizure medications in patients with refractory epilepsy ...
Wammes-van der Heijden, Elisabeth, van’ t Veer, Marcel; id_orcid, Dingen, Dennis; id_orcid, Lazeron, Richard H. C., Van' t Veer, Marcel, van Mastrigt, Ghislaine, van Mastrigt, Ghislaine; id_orcid, van’ t Veer, Marcel, Dingen, Dennis, Lazeron, Richard H.C., Majoie, Marian   +10 more
core   +1 more source

Psychiatric Implications of Anti-seizure Medications in Epileptic Population

BMC Neurology
Abstract BACKGROUND AND OBJECTIVE: Epilepsy is a common neurological complaint that is impacting millions of people worldwide. It's linked with a high frequency of psychiatric comorbidities, which can have a substantial impact on cases' living standards. The objective of this study was to probe the connotation between antiseizure treatments and
Bushra Khalid, Zaid Waqar, Soban Khan, Ijaz Ali, Naheed Afzal, Anum Irfan, Waleed Malik, Malik Muhammad Adil, Amina Saddiqa, Maryam Khalil, Zeeshan Munawar   +10 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source