Results 41 to 50 of about 1,348,208 (253)
M. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. [PDF]
PLoS Pathogens, 2007 Receptor Ser/Thr protein kinases are candidates for sensors that govern developmental changes and disease processes of Mycobacterium tuberculosis (Mtb), but the functions of these kinases are not established. Here, we show that Mtb protein kinase (Pkn) D
Andrew E Greenstein +5 more
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Communicative & Integrative Biology, 2023 Anti-sigma factor antagonists SpoIIAA and RsbV from Bacillus subtilis are the archetypes for single-domain STAS proteins in bacteria. The structures and mechanisms of these proteins along with their cognate anti-sigma factors have been well studied ...
Morgan E. Milton, Karen L. Visick
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The role of anti‐sigma factors in gene regulation [PDF]
Molecular Microbiology, 1995 SummaryDespite the isolation of an anti‐sigma factor over 20 years ago, it is only recently that the concept of an anti‐sigma factor emerged as a general mechanism of transcriptional regulation in prokaryotic systems. Anti‐sigma factors bind to sigma factors and inhibit their transcriptional activity.
K L, Brown, K T, Hughes
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Overproduction and Characterization of the Bacillus subtilis Anti-sigma Factor FlgM [PDF]
Journal of Biological Chemistry, 1999 FlgM is an anti-sigma factor of the flagellar-specific sigma (sigma) subunit of RNA polymerase in Bacillus subtilis, and it is responsible of the coupling of late flagellar gene expression to the completion of the hook-basal body structure. We have overproduced the protein in soluble form and characterized it.
M. G. Bertero +4 more
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Structural insights into the regulation of SigB activity by RsbV and RsbW
IUCrJ, 2020 Bacillus subtilis SigB is an alternative sigma factor that initiates the transcription of stress-responsive genes. The anti-sigma factor RsbW tightly binds SigB to suppress its activity under normal growth conditions and releases it when ...
Deepak Pathak +5 more
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Multiple σEcfG and NepR Proteins Are Involved in the General Stress Response in Methylobacterium extorquens. [PDF]
PLoS ONE, 2016 In Alphaproteobacteria, the general stress response (GSR) is controlled by a conserved partner switch composed of the sigma factor σ(EcfG), its anti-sigma factor NepR and the anti-sigma factor antagonist PhyR.
Anne Francez-Charlot +4 more
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Frontiers in Microbiology, 2020 It has been previously shown that RskA, the anti-Sigma factor K of Mycobacterium tuberculosis, inhibits SigK and that mutations in RskA promote high expression of the SigK regulon.
Frédéric J. Veyrier +11 more
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Characterization of five ECF sigma factors in the genome of Pseudomonas syringae pv. syringae B728a. [PDF]
PLoS ONE, 2013 Pseudomonas syringae pv. syringae B728a, a bacterial pathogen of bean, utilizes large surface populations and extracellular signaling to initiate a fundamental change from an epiphytic to a pathogenic lifestyle.
Poulami Basu Thakur +3 more
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STAS Domain Only Proteins in Bacterial Gene Regulation
Frontiers in Cellular and Infection Microbiology, 2021 Sulfate Transport Anti-Sigma antagonist domains (Pfam01740) are found in all branches of life, from eubacteria to mammals, as a conserved fold encoded by highly divergent amino acid sequences.
Brian E. Moy, J. Seshu
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Sigma factor-anti-sigma factor interaction in alginate synthesis: inhibition of AlgT by MucA [PDF]
Journal of Bacteriology, 1996 Conversion from the nonmucoid to the mucoid phenotype is a typical feature of Pseudomonas aeruginosa strains causing chronic pulmonary infections in cystic fibrosis patients. One of the key genetic controls in this conversion to mucoidy is from the algT(U)-mucA-mucB(algN) locus, located at 67.5 min on the standard P. aeruginosa chromosomal map.
Z D, Xie +4 more
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