Results 51 to 60 of about 56,069 (193)

A retrospective study of use of polyvalent anti-snake venom and risk factors for mortality from snake bite in a tertiary care setting

Indian Journal of Pharmacology, 2015
Aims: Envenomation with poisonous snakes is associated with considerable morbidity and mortality. The present study was undertaken with the objectives of assessing anti-snake venom (ASV) use, early adverse reactions to ASV, premedication and clinical ...
S. Pore, S. Ramanand, Praveen T. Patil, A. Gore, M. P. Pawar, S. Gaidhankar, Ravi R. Ghanghas   +6 more
semanticscholar   +1 more source

Artemia salina Toxicity Assay: Standardization in a 24‐Well Microplate

Environmental Toxicology, EarlyView.
ABSTRACT Bioassays with Artemia sp. are widely used in aquatic, environmental, and human toxicology as an initial tool to investigate the toxicity of plant extracts, isolated compounds, drugs, and products of natural or synthetic origin. These assays allow for the estimation of the median lethal concentration (LC50) and guide subsequent studies in ...
Matheus Pires Miranda, Natalie Petrovna Semanovschi, Roseane Santos de Souza, Angélica Maria Lucchese, Luzimar Gonzaga Fernandez   +4 more
wiley   +1 more source

Significant Far‐Right Challenges to Australian Society? The XYZ and AustraliaOne

Australian Journal of Politics &History, EarlyView.
ABSTRACT Scholars who analyse the Australian far‐right from a criminological or security studies perspective propose that activists and groups pose ‘political’ challenges to Australian society. This paper examines the far‐right news website The XYZ and the AustraliaOne political party, and argues that claims that the far‐right may normalise ...
Timothy Lynch
wiley   +1 more source

Anti-snake Venom Activity of Aqueous and Ethanolic Extracts of Crinum jagus Bulb

, 2018
Aim: To determine the anti-snake venom effect of crude aqueous and ethanolic extracts and separated fractions of Crinum jagus bulb on rats injected with Echis ocellatus venom.
A. H. Zailani, P. K. Magaji, S. Sarkiyayi, A. Wurochekke   +3 more
semanticscholar   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells

British Journal of Pharmacology, EarlyView.
Background and Purpose Colorectal cancer is one of the most prevalent cancers worldwide, and novel precision medicine approaches are rapidly improving patient outcomes. Phosphodiesterase 4B (PDE4B) is a member of an enzyme family (PDE4) that hydrolyses intracellular cAMP to control spatial and temporal signalling cues.
Alina Zorn, John Daniel Pediani, Madihah Hussain, Jiayue Ling, Elaine Brown, Igor Belka, Eduardo Torres, Cathy Swindlehurst, Kyle Chan, David Stirling, George S. Baillie, Yuan Yan Sin   +11 more
wiley   +1 more source

Shortcomings in snake bite management in rural Cameroon: a case report

BMC Research Notes, 2017
Background Snake bites are an important public health problem in developing countries with most bites occurring in rural areas. Severe envenomation often occurs in children and following bites to the face.
Frank-Leonel Tianyi, Christian Akem Dimala, Vitalis Fambombi Feteh   +2 more
doaj   +1 more source

Empirical use of anti-snake venom in the early morning neuroparalysis

Annals of Tropical Medicine and Public Health, 2013
Background: Snake bite is a common acute medical emergency, which can present with atypical symptoms in the pediatric age group. Objective: The objective of the present study is to determine the outcome of patients presenting in the early morning with acute onset of atypical symptoms, no history of snake bite or bite marks be considered as a snake bite
VinayakY Kshirsagar, Minhajuddin Ahmed, SylviaM Colaco   +2 more
openaire   +1 more source

Role of Anti Snake Venom in Snake Bite in Third Trimester of Pregnancy

International Journal of Medical and Pharmaceutical Case Reports, 2022
A case of pregnancy associated with neurotoxic snake bite presenting with Neuropathic symptoms and systemic envenomation complicated by disseminated intravascular bleeding is uncommon. We present a case of 22-year-old Primigravida at 32 weeks gestation with snake bite on left-hand, with left-hand swelling, nasal bleeding and neuropathic signs.
Sanchit Bhandari, Nitesh Jindal, Tanuraj Sirohi, Pediredla Sri Sowmya   +3 more
openaire   +1 more source

The effect of a serum containing acetyl hexapeptide‐8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies

International Journal of Cosmetic Science, EarlyView.
The novel serum demonstrates significant anti‐skin aging effects, effectively improving static and dynamic wrinkles and skin texture. Therefore, this formulation holds promise as a safe and effective product in the field of anti‐wrinkle skincare products.
Mingjie Zhu, Xiaofeng He, Zailing Zhu, Stephen Lynch, Hequn Wang, Xiaoyin Zhou, Yidong Tu, Andrew Steel, Kung Chi Hsu, Yueqing Niu, Anna Cho, Mutsue Hashimoto, Xi Yan, Maggie Su, Wenna Wang   +14 more
wiley   +1 more source