Results 11 to 20 of about 2,675,396 (301)

TNF-alpha in asthma

, 2007
Although only 5-10% of patients with asthma are relatively unresponsive to treatment with inhaled corticosteroids, refractory asthma represents an important condition as these patients suffer considerable morbidity and mortality and consume a ...
Ian D. Pavord (7582361), Andrew J. Wardlaw (7582364), Mike A. Berry (7582358), Christopher E. Brightling (7165121)   +3 more
core   +7 more sources

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

, 2019
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort ...
JC Mansfield (7655168), S Lin (3326841), P Dunckley (13556404), V Patel (7804106), T Mahmood (7810361), S Sonwalkar (13556410), MH Perry (15786794), NM Croft (15786839), DR Gaya (15786758), KJ Monahan (15786848), SL Bloom (15786836), JO Lindsay (14451168), R Nice (13556287), PS Babu (15786833), H Jafferbhoy (13556425), A Willmott (13556431), P Hendy (13556296), C Mowat (7776473), JS De Caestecker (15786830), S Sebastian (12221999), A Thomas (841916), J Lindsay (13386681), A Butt (6886730), C Bell (13305693), Neel Heerasing (13087041), CD Murray (15786851), S Bouri (12222098), CP Selinger (15786800), AT Cole (15786746), N Chanchlani (13556293), A Shenoy (13556377), TC Tham (15786806), T Orchard (13556467), S Murugesan (13556344), G Chung-Faye (100786), M Parkes (7655123), D Basude (13556350), M Harbord (13556449), A Hart (3561902), AVJ Gunasekera (15786815), R Miller (7753373), C Tzivinikos (13556437), GA Heap (15786737), S de Silva (10002803), TH Iqbal (15786809), S Weaver (7629431), JRF Cummings (15786797), C Lees (13556395), B Hope (13556452), J De La Revella Negro (13556365), V Kaushik (13556341), CU Nwokolo (15786818), B Hamilton (11794709), C Bewshea (5785718), GJ Walker (12222002), JR Goodhand (15786776), H Matthews (13433232), V Zamvar (12146040), L Gervais (13556401), S Singh (36962), RH Phillips (15786827), JW Hart (15786821), CE MacDonald (15786812), TJ McDonald (15786803), A Agrawal (7723772), R Shenderey (13556419), PJR Banim (15786824), R Hariraj (13556422), D Elphick (13556374), S Bridger (13556386), A Beale (13556353), NA Kennedy (12222005), B Colleypriest (13556332), D Ghosh (7940741), A Dhar (12222170), PM Irving (11289144), JM Fell (15786842), P Mayhead (13556392), AL Hart (15786761), RK Russell (7776491), D McGovern (13556320), CW Lees (7655129), L Armstrong (9149234), F Torrente (13556362), G Jones (2555320), J Doherty (7709057), N Direkze (13556359), A Thakur (9895997), S Langlands (13556356), Z Mazhar (13556326), JE Mawdsley (15786845), HD Green (15786791), SM Evans (14530529), A McNair (13556458), M Smith (7716890), SC Cooper (9947417), R Saich (13556329), C Preston (13556347), A Azaz (13556416), T Ahmad (5785727)   +99 more
core   +7 more sources

Development of psoriasis in IBD patients under TNF-antagonist therapy is associated neither with anti-TNF-antagonist antibodies nor trough levels [PDF]

, 2016
Background: The cause of anti-TNF-induced psoriasis is still unknown. Objective: We aimed to evaluate if the appearance of psoriasis under anti-TNF therapy is associated with anti-TNF antibody levels and TNF-antagonist trough levels.
Nikhil Yawalkar (2987304), Stephan Vavricka (2987307), Frank Seibold (197132), Alain Schoepfer (2987301), Marijana Protic (2987310)   +4 more
core   +2 more sources

Anti-TNF-alpha-induced lupus [PDF]

Arthritis Research & Therapy, 2019
Michel De Bandt
doaj   +3 more sources

Impact of treatment with immunomodulators and tumour necrosis factor antagonists on the incidence of infectious events in patients with inflammatory bowel disease

Upsala Journal of Medical Sciences, 2022
Background: Corticosteroids, immunomodulators (IM) and tumour necrosis factor antagonists (anti-TNF) are commonly used in the treatment of inflammatory bowel disease (IBD) but they also supress the defence against infectious disease.
Per Andersson, Pontus Karling
doaj   +1 more source

Anti-TNF Therapy

Microbiology Spectrum, 2016
ABSTRACTTumor necrosis factor (TNF) is one of the most important cytokines produced by macrophages. TNF is a very important component of host defense, released very rapidly after all types of injuries and stimuli. The kinetics of TNF release are short, and so it is perhaps not surprising that prolonged TNF production is associated with pathology.
Udalova, I., Monaco, C., Nanchahal, J. and Feldmann, M.   +6 more
openaire   +3 more sources

Regulatory T cells in Crohn's disease following anti‐TNF‐α therapy

JGH Open, 2020
Background and Aim Anti‐tumor necrosis factor alpha (TNF‐α) therapy is an effective therapy for Crohn's disease (CD). We investigated FoxP3+ and CD127− regulatory T cells (Tregs) before and after administration of anti‐TNF‐α therapy in CD.
Toshimi Chiba, Mikiya Endo, Shoko Miura, Yuko Hayashi, Yoshiko Asakura, Kotaro Oyama, Takayuki Matsumoto   +6 more
doaj   +1 more source

Using cardiovascular magnetic resonance to define mechanisms of comorbidity and to measure the effect of biological therapy: the CADERA observational study

Efficacy and Mechanism Evaluation, 2021
Background: The VEDERA (Very Early vs. Delayed Etanercept in Rheumatoid Arthritis) randomised controlled trial compared the effect of conventional synthetic disease-modifying anti-rheumatic drug (csDMARD) therapy with biologic DMARD (bDMARD) therapy ...
Sven Plein, Bara Erhayiem, Graham Fent, Jacqueline Andrews, John Greenwood, Paul Baxter, Elizabeth M Hensor, Sue Pavitt, Maya H Buch   +8 more
doaj   +1 more source

Anti-TNF-induced lupus [PDF]

Rheumatology, 2009
The use of protein-based anti-TNF-alpha therapies such as antibodies and soluble TNF-alpha receptors is commonly associated with the induction of autoantibodies, whereas anti-TNF-induced lupus (ATIL) is rare. ATIL can occur with any of the available TNF inhibitors, but the frequency and clinical characteristics of ATIL vary between different drugs ...
Williams, Emma L., Gadola, Stephen, Edwards, Christopher J.   +2 more
openaire   +3 more sources

Parasite genetic diversity does not influence TNF-mediated effects on the virulence of primary rodent malaria infections [PDF]

, 2006
The pro-inflammatory cytokine tumour necrosis factor alpha (TNF-alpha) is associated with malaria virulence (disease severity) in both rodents and humans.
Long, G H, Read, A F, Read, A. F., Chan, Brian, Long, G. H., Graham, Andrea, A. F. READ, G. H. LONG, Allen, J. E., Chan, B H K, A. L. GRAHAM, J. E. ALLEN, Allen, Judith, Graham, A. L., Allen, J E, Graham, A L, B. H. K. CHAN, Read, Andrew F, Chan, B. H K; id_orcid, Long, Gráinne Helen   +19 more
core   +1 more source