Results 71 to 80 of about 3,031 (126)

Synthesis and biological evaluation of imidamide analogs as selective anti-trypanosomal agents. [PDF]

Bioorg Med Chem, 2022
Bobba V, Li Y, Afrin M, Dano R, Zhang W, Li B, Su B.   +6 more
europepmc   +1 more source

In vitro anti-trypanosomal effect of ivermectin on Trypanosoma evansi by targeting multiple metabolic pathways. [PDF]

Trop Anim Health Prod, 2022
Gupta S, Vohra S, Sethi K, Gupta S, Bera BC, Kumar S, Kumar R.   +6 more
europepmc   +1 more source

KBE009: A Bestatin-Like Inhibitor of the Trypanosoma cruzi Acidic M17 Aminopeptidase with In Vitro Anti-Trypanosomal Activity. [PDF]

Life (Basel), 2021
González-Bacerio J, Arocha I, Aguado ME, Méndez Y, Marsiccobetre S, Izquierdo M, Rivera DG, Figarella K, Uzcátegui NL.   +8 more
europepmc   +1 more source

Sponge-associated sp. RM66 metabolome induction with N-acetylglucosamine: Antibacterial, antifungal and anti-trypanosomal activities. [PDF]

Saudi J Biol Sci, 2021
Alkhalifah DHM.
europepmc   +1 more source

Trypanocidal potentials of Jatropha curcas L. 1753 leaf extracts and fractions in vivo

Pharmacological Research - Modern Chinese Medicine
Introduction: Trypanosomiasis is a debilitating parasitic disease affecting both humans and animals, leading to substantial economic losses in the livestock sector due to reduced productivity and increased mortality.
Haolat Yusuf, Abdulhakeem Binhambali, Mutiu Olawale Rahmon, Ridwan Bolaji Yusuf, Suleiman Garba Salihu, Barnabas Jarumi Musa   +5 more
doaj   +1 more source

Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones

Molecules
2,6-Diaryl-4H-tetrahydro-thiopyran-4-ones and corresponding sulfoxide and sulfone derivatives were designed to lower the major toxicity of their parent anti-kinetoplatidal diarylideneacetones through a prodrug effect.
Thibault Gendron, Don Antoine Lanfranchi, Nicole I. Wenzel, Hripsimée Kessedjian, Beate Jannack, Louis Maes, Sandrine Cojean, Thomas J. J. Müller, Philippe M. Loiseau, Elisabeth Davioud-Charvet   +9 more
doaj   +1 more source

Targeted Isolation of Anti-Trypanosomal Naphthofuran-Quinone Compounds from the Mangrove Plant Avicennia lanata. [PDF]

Mar Drugs, 2020
Mazlan NW, Clements C, Edrada-Ebel R.
europepmc   +1 more source

Design, Synthesis, and Evaluation of Novel Anti-Trypanosomal Compounds. [PDF]

Tetrahedron, 2020
Lepovitz LT, Meis AR, Thomas SM, Wiedeman J, Pham A, Mensa-Wilmot K, Martin SF.   +6 more
europepmc   +1 more source

Individual and combined anti-trypanosomal effects of arteether and diminazene aceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats. [PDF]

Vet World, 2020
Egbe-Nwiyi TN, Abalaka SE, Sani NA, Tenuche OZ, Idoko IS.   +4 more
europepmc   +1 more source

Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model. [PDF]

PLoS One, 2020
Ndung'u K, Murilla GA, Thuita JK, Ngae GN, Auma JE, Gitonga PK, Thungu DK, Kurgat RK, Chemuliti JK, Mdachi RE.   +9 more
europepmc   +1 more source