In Vivo Anti-Trypanosomal Activity of Basil Extract on Trypanosoma evansi
E. Razin+4 more
semanticscholar +1 more source
Front-line glioblastoma chemotherapeutic temozolomide is toxic to Trypanosoma brucei and potently enhances melarsoprol and eflornithine [PDF]
Sleeping sickness is an infectious disease that is caused by the protozoan parasite Trypanosoma brucei. The second stage of the disease is characterised by the parasites entering the brain.
Rushworth, Stuart A.+1 more
core +1 more source
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]
Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Alonso-Padilla, Julio+20 more
core +2 more sources
Anti-trypanosomal activities of polyherbal formulation of Lawsonia inermis and Azadiractha indica when combined with diminazene aceturate [PDF]
Abdulfatai Aremu+6 more
openalex +1 more source
Synthesis, antiprotozoal activity and cytotoxicity in U-937 macrophages of triclosan–hydrazone hybrids [PDF]
The synthesis and biological activities (cytotoxicity, leishmanicidal, and trypanocidal) of 11 triclosan–hydrazone hybrids are described herein. The structure of the products was elucidated by spectral data (NMR, IR) and mass spectrometric analyses.
Iván D. Vélez+6 more
core +3 more sources
Trypanosoma equiperdum in the horse : a neglected threat? [PDF]
Dourine is a contagious disease caused by Trypanosoma equiperdum that is transmitted directly from animal to animal during coitus. Dourine is known as an important disease in many countries, and it threatens equidae worldwide.
Ahmed, Y+6 more
core
Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport [PDF]
. Lipoprotein lipase (LPL) and glycolipidanchored cAMP-binding ectoprotein (Gcel) are modified by glycosyl-phosphatidylinositol (GPI) in rat adipocytes, however, the linkage is potentially unstable. Incubation of the cells with either insulin (0.1-30 nM)
Bandlow, Wolfhard+3 more
core +3 more sources
The Inhibition of the Anti-Trypanosomal Activity of Arsenoso Compounds and Acridines by Esters and Amides of Organic Acids [PDF]
W. L. Schleyer, R. Schnitzer
openalex +1 more source
Anti-trypanosomal effects of aqueous extract of Ocimum gratissimum (Lamiaceae) leaf in rats infected with Trypanosoma brucei brucei [PDF]
The anti-trypanosomal effects of aqueous extract of the leaf of Ocimum gratissimum were evaluated in both in-vitro and in-vivo studies. The anti-trypanosomal activity of the extract against Trypanosoma brucei was investigated in-vitro.
Adamu, M, Agbede, R, Nwosu, C.O
core +2 more sources
ANTI‐TRYPANOSOMAL ACTIVITY OF CERTAIN PHENYLDIAZOAMINO‐ AND PHENYLAZOAMINO‐PHENANTHRIDINIUM COMPOUNDS [PDF]
K. N. Brown+2 more
openalex +1 more source