Pharmaceutical Biology, 2010 The activity of an (8-hydroxymethylen)-trieicosanyl acetate compound obtained from chloroform extracts of Senna villosa (Mill.) H.S. Irwin & Barneby (Leguminosae) against Trypanosoma cruzi was evaluated in vivo. Oral doses of 2.1, 8.4, and 33.6 microg/g were tested for 28 days in BALB/c mice infected with T. cruzi.
Matilde, Jimenez-Coello +4 more
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Structural Characterization of Acidic M17 Leucine Aminopeptidases from the TriTryps and Evaluation of Their Role in Nutrient Starvation in Trypanosoma brucei [PDF]
, 2017 Leucine aminopeptidase (LAP) is found in all kingdoms of life and catalyzes the metal-dependent hydrolysis of the N-terminal amino acid residue of peptide or amino acyl substrates.
Alvarez +63 more
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Molecules2,6-Diaryl-4H-tetrahydro-thiopyran-4-ones and corresponding sulfoxide and sulfone derivatives were designed to lower the major toxicity of their parent anti-kinetoplatidal diarylideneacetones through a prodrug effect.
Thibault Gendron +9 more
doaj +1 more source
Establishment of a tRNA over-expression system in Trypanosoma brucei to study the role of post-transcriptional modifications on function. [PDF]
, 2007 Undergraduate Research ScholarshipMayers Summer InternshipDean's Undergraduate Research FundTrypanosomatids are parasitic protozoa which infect millions of humans and animals across the globe every year.
Fill, Mary-Margaret
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Anti-trypanosomal Activity of Endophytic Streptomycete
Current Research in Bacteriology, 2010 N.M. Zin +4 more
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Anti-trypanosomal antibodies in sequentially collected sera of N'Dama cattle under natural trypanosomiasis risk in The Gambia [PDF]
, 2014 Investigates the time of appearance and the persistence of antibodies in N'Dama cattle bitten by infected tsetse flies under controlled conditions, the serology of village animals exposed to natural trypanosomiasis risk and the time of appearance and ...
Agyemang, K. +4 more
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Two lipid-anchored cAMP-binding proteins in the yeast Saccharomyces cerevisiae are unrelated to the R subunit of cytoplasmic protein kinase A [PDF]
, 1991 Bandlow, Wolfhard, Müller, Günter
core +1 more source
Glucose induces lipolytic cleavage of a glycolipidic plasma membrane anchor in yeast [PDF]
, 1993 Bandlow, Wolfhard, Müller, Günter
core +2 more sources
In vitro and in vivo Anti Trypanosomal Activity of the Leaf of Lawsonia inermis Against Trypanosoma brucei brucei Infection in Mice [PDF]
, 2004 A. U. Wurochekke +2 more
openalex +1 more source