Results 81 to 90 of about 2,622 (160)

Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin

Journal of Molecular Biology, 2005
Suramin, a synthetic polysulfonated compound, developed initially for the treatment of African trypanosomiasis and onchocerciasis, is currently used for the treatment of several medically relevant disorders. Suramin, heparin, and other polyanions inhibit the myotoxic activity of Lys49 phospholipase A2 analogues both in vitro and in vivo, and are thus ...
Murakami, M. T., Arruda, E. Z., Melo, P. A., Martinez, A. B., Calil-Elias, S., Tomaz, M. A., Lomonte, B., Gutierrez, J. M., Arni, R. K.   +8 more
openaire   +4 more sources

Anti-trypanosomal Activity of Endophytic Streptomycete

Current Research in Bacteriology, 2010
N.M. Zin, K.T. Ng, N.M. Sarmin, K. Getha, G.Y. Tan   +4 more
openaire   +1 more source

In Vivo Anti-Trypanosomal Activity of Basil Extract on Trypanosoma evansi

Advances in Animal and Veterinary Sciences, 2023
Esam A Razin, Hassan Sobhy, Tarek R. AboElnaga, Asmaa A. Darwish, Rasha S. Mohammed   +4 more
openaire   +1 more source

In Vivo anti-trypanosomal activity of dichloromethane and methanol crude leaf extracts of Dovyalis abyssinica (Salicaceae) against Trypanosoma congolense. [PDF]

BMC Complement Altern Med, 2015
Tadesse B, Terefe G, Kebede N, Shibeshi W.   +3 more
europepmc   +1 more source

Anti-trypanosomal Activity of Potential Inhibitors of Trypanosoma brucei Glycolytic Pathway Enzymes Selected by Docking Studies

Rwanda Medical Journal, 2014
Human African trypanosomiasis (HAT), a potentially fatal protozoan infection caused by tsetse-fl mediated transmission of Trypanosoma brucei (T. Brucei), is largely recognized as a neglected disease.
Clarisse Musanabaganwa, Fidele Byiringiro   +1 more
doaj  

Human Histatin 5 Exerts Anti-Trypanosomal Activity Against <i>Trypanosoma cruzi</i> and Induces Ultrastructural Damage, Apoptosis-like Cell Death, and Oxidative/Nitrosative Stress. [PDF]

Int J Mol Sci
Blancas-Luciano BE, Becker I, Sánchez-Chávez MA, Gómez-Guzmán A, Lara-Martínez R, Jiménez-García LF, Zamora-Chimal J, Delgado-Dominguez J, Fernández-Presas AM.   +8 more
europepmc   +1 more source

Alkyl gallates disrupt Trypanosoma brucei lipid droplets. [PDF]

PLoS One
Amisigo CM, Amegatcher G, Sunter JD, Gwira TM.   +3 more
europepmc   +1 more source

Anti-trypanosomal, anti-inflammatory, and neuroprotective effects of Cichorium intybus sesquiterpene lactones in experimental Trypanosoma evansi infection. [PDF]

Sci Rep
Sawerus MG, Kamel HH, Ahmed WMS, Abdel-Shafy S, El Amir D, Mahdi EA, Ibrahim MA, Shehata O.   +7 more
europepmc   +1 more source

The β2αB loop determines NAD(P) cofactor specificity and kinetics in trypanosomal D-3-hydroxybutyrate dehydrogenases. [PDF]

J Mol Biol
Hashimoto H, Mawn IH, Escobar-Arrillaga W, Nguyen L, Madigan LA, Antuono G, Rossy T, Sojati J, Mienko A, Debler EW, Palenchar JB.   +10 more
europepmc   +1 more source

<i>Trypanosoma evansi</i>: Molecular Characterization and Validation of a Cathepsin-L-like Peptidase as a Potential Therapeutic Target. [PDF]

Pathogens
Bremo A, Pérez YG, Turcios LM, Caffrey CR, Bogyo M, McKerrow JH, Gonzatti M.   +6 more
europepmc   +1 more source