Results 1 to 10 of about 396,796 (347)

Crossword puzzles as a tool to enhance learning about anti-ulcer agents. [PDF]

open access: greenAm J Pharm Educ, 2010
To design, implement, and evaluate the use of crossword puzzles as a low-stakes educational tool for enhancing learning about anti-ulcer agents.Crossword puzzles were created using a free Internet resource and administered to students during 3 consecutive lectures covering the pharmacology and medicinal chemistry of anti-ulcer agents.
Shah S, Lynch LM, Macias-Moriarity LZ.
europepmc   +5 more sources

ANTI-ULCER AGENTS: A PHARMACOLOGICAL UPDATE OF THE PAST TEN YEARS

open access: yesAsian Journal of Pharmaceutical and Clinical Research, 2019
New anti-ulcer substances are still vitally necessary for the people of countries such as India and South Africa to avoid high cost of the most prescribed marketed anti-ulcer drugs (proton-pump inhibitors). New candidate against gastric ulcer is also necessary to avoid the potential problem (enterochromaffin-like cell hyperplasia may be induced ...
Subhojit Dawn   +2 more
openaire   +3 more sources

Synthesis, characterization, anti-ulcer action and molecular docking evaluation of novel benzimidazole-pyrazole hybrids

open access: yesChemistry Central Journal, 2017
A series of six novel benzimidazole-pyrazole hybrid molecules was synthesized and characterized using elemental analysis (CHN) and spectroscopic methods (1HNMR, FT-IR).
Abida Noor   +6 more
doaj   +2 more sources

Scope of medicinal flora as effective anti ulcer agents

open access: yesAfrican Journal of Plant Science, 2013
Gastric ulcer generally results from persistent erosions and damage of the stomach wall which become perforated and develops into peritonitis and massive haemorrhage as a result of inhibition of the synthesis of mucus, bicarbonate and prostaglandins. The commercially available antiulcer drugs usually have various side effects. Due to these side effects,
Swapna Reddy   +4 more
openaire   +4 more sources

Studies on anti-ulcer agents. II. Synthesis and anti-ulcer activities of 6-isopropylazulene-1-sodium sulfonate derivatives.

open access: yesChemical and Pharmaceutical Bulletin, 1990
A series of alkylazulene-1-sodium sulfonate derivatives which has an isopropyl group at 6-position were synthesized, and their anti-ulcer activities were examined in Shay pylorus-ligated rats. The values of lipophilicity (log P) as a parameter of these new azulene derivatives were also examined in reference to the structure-activity relationship.
Kazuhiro Kosakai   +4 more
openaire   +5 more sources

Cytoprotective Effect of SU-88, an Anti-Ulcer Agent, in the Rat

open access: goldJapanese Journal of Pharmacology, 1984
The gastric cytoprotective action of SU-88, an anti-ulcer agent, was studied in rats. SU-88 dose-dependently prevented the formation of gastric lesions induced by absolute ethanol as observed by PGE2. The efficacy of SU-88 when given i.p. was more potent than the p.o. administration.
Toshio Suwa   +4 more
openalex   +5 more sources

IN SILICO PHARMACOKINETIC, BIOACTIVITY AND TOXICITY EVALUATION OF SOME SELECTED ANTI-ULCER AGENTS

open access: yesInternational Journal of Pharmaceutical Sciences and Drug Research, 2017
Peptic ulcer is a major health burden that recognized as a group of upper gastro-intestinal tract disorders. The aim of the therapy is to provide relieve from pain and prevent ulcer complications. Therefore, it is essential to evaluate the drug-likeness and toxicity profile of existing drugs for developing new potent anti-ulcer agents. In this research
Hamendra Pratap Singh   +4 more
openaire   +3 more sources

Simultaneous Evaluation of Gastric and Duodenal Ulcers-Healing Activities of Anti-ulcer Agents in Rats.

open access: yesBiological and Pharmaceutical Bulletin, 1996
We investigated the effects of cimetidine, omeprazole and atropine, antisecretory anti-ulcer agents, on the healing of gastric and duodenal ulcers simultaneously induced in the same rats. Furthermore, we examined the effect of histamine, an acid secretory agent, on the healing of both ulcers. When the effects of test drugs were assessed on the 15th day
Tetsuya Segami, Mikio Ito, Yoshio Suzuki
openaire   +5 more sources

A facile synthesis of aminocarboxylic acid derivatives, new anti-ulcer agents.

open access: bronzeChemischer Informationsdienst, 1985
AbstractDie aus den Carbonsäuren (I) hergestellten Säurechloride werden nach Friedel‐ Crafts mit (II) zu den Estern (III) umgesetzt, die mit Salzsäure zu den freien Säuren (IV) verseift werden.
Toru Takeshita   +2 more
openalex   +5 more sources

Changes in Synthetic Activity of Sulfated Mucosubstances in Healing Process of Acetic Acid Ulcer in Rats and Effect of Anti-Ulcer Agents

open access: goldJapanese Journal of Pharmacology, 1984
It is generally believed that ulcerogenesis results from an imbalance between the aggressive and defensive factors (1). Recently, increasing interest is being shown regarding the importance of anti-ulcer therapy, presumably via the positive effects on ...
Toshio Suwa   +3 more
openalex   +2 more sources

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