The Ugi-azide MCR (UA) is one of the most efficient methods for the synthesis of 1,5-disubstituted-1H-tetrazoles (1,5-DS-T). Complex drug-like scaffolds incorporating tetrazoles have demonstrated a wide range of therapeutic benefits such as anti ...
Alejandro Corona-Díaz+4 more
doaj +1 more source
Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam+3 more
core +3 more sources
Mycobacterium ulcerans infection: control, diagnosis, and treatment. [PDF]
The skin disease Buruli ulcer, caused by Mycobacterium ulcerans, is the third most common mycobacterial disease after tuberculosis and leprosy and mainly affects remote rural African communities. Although the disease is known to be linked to contaminated
Adjei+64 more
core +2 more sources
Topical therapy for complex treatment of chronic venous insufficiency
This article presents a review of the current literature on the problem of topical therapy in the complex treatment of chronic venous insufficiency. The relevance of the study of this pathology is due to the prevalence of the disease in the world and in ...
S. S. Dunaevskaya
doaj +1 more source
Clinical characteristics and poor predictors of anti-NXP2 antibody-associated Chinese JDM children
Background Juvenile dermatomyositis (JDM) is a rare and sometimes fatal disease in children. The anti-NXP2 antibody is one of the most common antibodies and muscle ischaemia associated with NXP2 autoantibodies was a severe subtype of JDM.
Xinning Wang+5 more
doaj +1 more source
The evidence supporting the use of honey as a wound dressing [PDF]
Some clinicians are under the impression that there is little or no evidence to support the use of honey as a wound dressing. This impression is reinforced by it being concluded in systematic reviews that the evidence is not of a high standard.
Molan, Peter C.
core +2 more sources
Clinical Guidelines for Drug-Related Peptic Ulcer, 2020 Revised Edition
Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcer were previously developed in 2009 with the collaboration of the Korean College of Helicobacter and Upper Gastrointestinal Research and Korean Society of ...
Moon Kyung Joo+14 more
doaj +1 more source
Antibiotic susceptibility, heteroresistance, and updated treatment strategies in helicobacter pylori infection [PDF]
In this review, we discuss the problem of antibiotic resistance, heteroresistance, the utility of cultures and antibiotic susceptibility tests in Helicobacter pylori (Hp) eradication, as well as the updated treatment strategies for this infection.
De Angelis, Massimiliano+3 more
core +1 more source
Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease [PDF]
Buruli ulcer is a skin disease caused by Mycobacterium ulcerans that is spreading in tropical countries, with major public health and economic implications in West Africa.
AA Pahlevan+48 more
core +9 more sources
Survey of general practitioners' knowledge about Helicobacter pylori infection [PDF]
BACKGROUND: Helicobacter pylori, occurring throughout the world and causing gastroduodenal diseases, is one of the most common chronic bacterial agents in humans.
Canbaz, Sevgi+3 more
core +3 more sources