Results 71 to 80 of about 39,168 (176)

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, Volume 3, Issue 2, Page 87-101, June 2026.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Efficacy of antituberculosis therapy in combination with antiretroviral therapy in patients with co-infection TB/HIV [PDF]

Medičnì Perspektivi, 2013
Changes towards worsening of epidemiologic situation as for tuberculosis in a great extent are caused by spread of HIV-infection among population of Ukraine.
Kryzhanovsky D.G., Marchenko N.A.
doaj  

Miopericarditis como complicación cardiovascular en la infección por VIH.

Revista GICOS, 2021
Introducción: Las complicaciones cardiovasculares son actualmente una causa principal de morbilidad y mortalidad en la población infectada por el Virus de Inmunodeficiencia Humana (VIH), sobre todo en los países subdesarrollados.
Luis Dulcey, Jonathan Pineda, José Sampayo, Raimondo Caltagirone   +3 more
doaj  

In vivo anti-HIV activity of the heparin-activated serine protease inhibitor antithrombin III encapsulated in lymph-targeting immunoliposomes.

PLoS ONE, 2012
Endogenous serine protease inhibitors (serpins) are anti-inflammatory mediators with multiple biologic functions. Several serpins have been reported to modulate HIV pathogenesis, or exhibit potent anti-HIV activity in vitro, but the efficacy of serpins ...
Mohammed Asmal, James B Whitney, Corinne Luedemann, Angela Carville, Robert Steen, Norman L Letvin, Ralf Geiben-Lynn   +6 more
doaj   +1 more source

Public Health Achievements in Rwanda: A 21st Century Transformation

Public Health Challenges, Volume 5, Issue 2, June 2026.
This narrative review examines Rwanda's post‐2000 public health transformation using the WHO health system building blocks. It shows how strategic governance, universal health coverage via mutuelle de santé, community health workers, and digital health tools have driven substantial gains in maternal/child health, infectious disease control, and ...
Niyibizi Julius, Mugisha John, Nizeyimana Emmanuel   +2 more
wiley   +1 more source

Impact of interrupting antiretroviral therapy started during primary HIV-1 infection on plasma neurofilament light chain protein, a marker of neuronal injury: The SPARTAC trial

Journal of Virus Eradication
Objective: Antiretroviral therapy (ART)-conferred suppression of HIV replication limits neuronal injury and inflammation. ART interruption tests efficacy in HIV cure trials and viral rebound after ART interruption may induce neuronal injury.
Jasmini Alagaratnam, Wolfgang Stöhr, Elizabeth Hamlyn, Kholoud Porter, Jamie Toombs, Amanda Heslegrave, Henrik Zetterberg, Magnus Gisslén, Jonathan Underwood, Mauro Schechter, Pontiano Kaleebu, Giuseppe Tambussi, Sabine Kinloch, Jose M. Miro, Anthony D. Kelleher, Abdel Babiker, John Frater, Alan Winston, Sarah Fidler   +18 more
doaj   +1 more source

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites.

PLoS ONE, 2015
Cancer cells have a high iron requirement and many experimental studies, as well as clinical trials, have demonstrated that iron chelators are potential anti-cancer agents.
Eliška Potůčková, Jaroslav Roh, Miloslav Macháček, Sumit Sahni, Ján Stariat, Vít Šesták, Hana Jansová, Pavlína Hašková, Anna Jirkovská, Kateřina Vávrová, Petra Kovaříková, Danuta S Kalinowski, Des R Richardson, Des R Richardson, Tomáš Šimůnek   +14 more
doaj   +1 more source

Defining and Predicting HIV Immunological Non-Response: A Multi-Definition Analysis from an Indonesian Cohort

Viruses
Immunological non-response (INR) to antiretroviral therapy (ART) is a critical concern for PLHIV, characterized by inadequate CD4+ T-cell recovery despite virological suppression.
Brian Eka Rachman, Yehuda Tri Nugroho Supranoto, Soraya Isfandiary Iskandar, Tri Pudy Asmarawati, Siti Qamariyah Khairunisa, Muhammad Vitanata Arfijanto, Usman Hadi, Muhammad Miftahussurur, Nasronudin Nasronudin, Masanori Kameoka, Retno Pudji Rahayu, Afif Nurul Hidayati   +11 more
doaj   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source

Utilização dos registros de dispensação da farmácia como indicador da não-adesão à terapia anti-retroviral em indivíduos infectados pelo HIV Pharmacy records as an indicator of non-adherence to antiretroviral therapy by HIV-infected patients

Cadernos de Saúde Pública, 2009
Este estudo teve como objetivos avaliar os registros de dispensação de anti-retrovirais (ARV) por um período de 12 meses após a primeira prescrição e determinar os fatores associados com a retirada irregular ou abandono em dois serviços públicos de ...
Raquel Regina de Freitas Magalhães Gomes, Carla Jorge Machado, Francisco de Assis Acurcio, Mark Drew Crosland Guimarães   +3 more
doaj   +1 more source