Results 41 to 50 of about 1,022,019 (313)
NON-ANTIBIOTIC USE OF ANTIBIOTICS [PDF]
Postępy Mikrobiologii - Advancements of Microbiology, 2018 Abstract Antibiotics are widely used medicines in the treatment of infectious diseases. However, some of them show also non-antibiotic properties, which are increasingly used in the treatment of non-infectious diseases. The authors of this publication believe that this is one of the reasons behind antibiotic dissemination in the ...
Dorota Ksiądzyna +2 more
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Nature CommunicationsMicrobial Ni2+ homeostasis underpins the virulence of several clinical pathogens. Ni2+ is an essential cofactor in urease and [NiFe]-hydrogenases involved in colonization and persistence.
David Sychantha +4 more
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Frontiers in Microbiology, 2020 Microbial natural products have been a cornerstone of the pharmaceutical industry, but the supply of novel bioactive secondary metabolites has diminished due to extensive exploration of the most easily accessible sources, namely terrestrial Streptomyces ...
Soheila Matroodi +6 more
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Unraveling the Diversity of Co-Colonization by CPE
Microorganisms, 2022 Antibiotic-resistant bacteria, and more specifically, carbapenem-producing Enterobacterales (CPE) strains, are increasing worldwide. Despite their growing prevalence, in most high-income countries, the detection of CPE is still considered a low-frequency
Gabrielle Levi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Active surveillance for carbapenem-resistant Acinetobacter baumannii (CRAB) carriage
Microbiology Spectrum, 2023 Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a significant threat in healthcare settings, necessitating robust infection control measures. To identify the most effective sampling method for CRAB carriage detection, we conducted a comparative
Amir Nutman +6 more
doaj +1 more source
Antibiotics and Environment [PDF]
Antibiotics, 2020 Since the discovery of penicillin by Alexander Fleming in 1928, the use of antibiotics has become the golden standard in the treatment of bacterial infections of all kinds [...]
openaire +4 more sources
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Flexible nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis
eLife, 2019 Bacterial metabolism is fundamental to survival and pathogenesis. We explore how Mycobacterium tuberculosis utilises amino acids as nitrogen sources, using a combination of bacterial physiology and stable isotope tracing coupled to mass spectrometry ...
Aleksandra Agapova +6 more
doaj +1 more source