Results 21 to 30 of about 4,390,699 (400)
Antimicrobial Resistance and Infection Control, 2022 Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E.
Sarah F. Feldman +8 more
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A framework for identifying the recent origins of mobile antibiotic resistance genes
Communications Biology, 2021 Ebmeyer and colleagues developed a genomic framework for identification and scrutiny of the origins of antibiotic resistance genes. Using data scoured from the literature and publicly available genomes, their results indicate that only 81% of previously ...
Stefan Ebmeyer +2 more
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Antimicrobial Resistance and Infection Control, 2023 Background Due to the substantial increase in the use of disinfectants containing quaternary ammonion compounds (QACs) in healthcare and community settings during the COVID-19 pandemic, there is increased concern that heavy use might cause bacteria to ...
J. Boyce
semanticscholar +1 more source
Resistance-resistant antibiotics [PDF]
Trends in Pharmacological Sciences, 2014 New antibiotics are needed because drug resistance is increasing while the introduction of new antibiotics is decreasing. We discuss here six possible approaches to develop 'resistance-resistant' antibiotics. First, multitarget inhibitors in which a single compound inhibits more than one target may be easier to develop than conventional combination ...
Eric Oldfield, Xinxin Feng
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Microbiome, 2020 Background New antibiotic resistance determinants are generally discovered too late, long after they have irreversibly emerged in pathogens and spread widely.
Maria-Elisabeth Böhm +4 more
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Assessment of global health risk of antibiotic resistance genes
Nature Communications, 2022 Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in the last decade. Many genes can confer resistance, but evaluating the relative health risks of ARGs is complex. Factors such as the abundance, propensity for lateral
Zhenyan Zhang +10 more
semanticscholar +1 more source
Antibiotic resistance: The challenges and some emerging strategies for tackling a global menace
Journal of clinical laboratory analysis (Print), 2022 Antibiotic resistance is currently the most serious global threat to the effective treatment of bacterial infections. Antibiotic resistance has been established to adversely affect both clinical and therapeutic outcomes, with consequences ranging from ...
David Chinemerem Nwobodo +6 more
semanticscholar +1 more source
Antibiotic Resistance in Bacteria—A Review
Antibiotics, 2022 Background: A global problem of multi-drug resistance (MDR) among bacteria is the cause of hundreds of thousands of deaths every year. In response to the significant increase of MDR bacteria, legislative measures have widely been taken to limit or ...
R. Urban-Chmiel +6 more
semanticscholar +1 more source
Bacterial Antibiotic Resistance: The Most Critical Pathogens
Pathogens, 2021 Antibiotics have made it possible to treat bacterial infections such as meningitis and bacteraemia that, prior to their introduction, were untreatable and consequently fatal.
G. Mancuso +3 more
semanticscholar +1 more source
Phenotypic Resistance to Antibiotics [PDF]
Antibiotics, 2013 The development of antibiotic resistance is usually associated with genetic changes, either to the acquisition of resistance genes, or to mutations in elements relevant for the activity of the antibiotic. However, in some situations resistance can be achieved without any genetic alteration; this is called phenotypic resistance. Non-inherited resistance
Fernando Corona, Jose Martinez
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