Minimizing treatment-induced emergence of antibiotic resistance in bacterial infections
Treatment of bacterial infections currently focuses on choosing an antibiotic that matches a pathogen’s susceptibility, with less attention paid to the risk that even susceptibility-matched treatments can fail as a result of resistance emerging in ...
Mathew Stracy +14 more
semanticscholar +1 more source
The WHO AWaRe (Access, Watch, Reserve) antibiotic book and prevention of antimicrobial resistance
Guidance on the appropriate use of antibiotics for common infections is lacking in many settings. The World Health Organization (WHO) has recently released The WHO AWaRe (Access, Watch, Reserve) antibiotic book which complements the WHO Model list of ...
V. Zanichelli +11 more
semanticscholar +1 more source
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
The Comprehensive Antibiotic Resistance Database (CARD; https://card.mcmaster.ca) is a curated resource providing reference DNA and protein sequences, detection models and bioinformatics tools on the molecular basis of bacterial antimicrobial resistance (
Brian P. Alcock +33 more
semanticscholar +1 more source
Bacterial Antibiotic Resistance: The Most Critical Pathogens
Antibiotics have made it possible to treat bacterial infections such as meningitis and bacteraemia that, prior to their introduction, were untreatable and consequently fatal.
G. Mancuso +3 more
semanticscholar +1 more source
The impact of antibiotic use on transmission of resistant bacteria in hospitals: Insights from an agent-based model [PDF]
Extensive antibiotic use over the years has led to the emergence and spread of antibiotic resistant bacteria (ARB). Antibiotic resistance poses a major threat to public health since for many infections antibiotic treatment is no longer effective ...
DRIVE-AB consortium +5 more
core +2 more sources
Background Colistin is still a widely used antibiotic in veterinary medicine although it is a last-line treatment option for hospitalized patients with infections caused by multidrug-resistant Gram-negative bacteria.
Bernd Neumann +5 more
doaj +1 more source
Carbapenemase-producing Enterobacteriaceae isolates collected in Portuguese hospitals [PDF]
Objectives: In Portugal, little is known on carbapenemase (CARB)-producing Enterobacteriaceae. The aim of this study was to identify the resistance mechanisms of Enterobacteriaceae isolates, identified at hospital laboratories as carbapenem (CA) non ...
Antibiotic Resistance Surveillance Program in Portugal (ARSIP) +4 more
core +1 more source
Antibiotic Resistance: One Health One World Outlook
Antibiotic resistance (ABR) is a growing public health concern worldwide, and it is now regarded as a critical One Health issue. One Health’s interconnected domains contribute to the emergence, evolution, and spread of antibiotic-resistant microorganisms
B. Aslam +11 more
semanticscholar +1 more source
Antimicrobial Resistance: An Update from the Canadian Committee on Antibiotic Resistance
The present article is one of a series prepared by the Canadian Committee on Antibiotic Resistance (CCAR). These articles are designed to update readers on current activities intended to limit the development and transmission of antibiotic resistance
Canadian Committee on Antibiotic Resistance
doaj +1 more source
Acinetobacter baumannii Bloodstream Infections: A Nationwide Study in Israel
Acinetobacter baumannii (Ab) bloodstream infections (BSIs) are a major public health concern and associated with high mortality. We describe the nationwide incidence, antimicrobial resistance, and mortality of Ab-BSI in Israel using laboratory-based BSI ...
Amir Nutman +5 more
doaj +1 more source

