Results 131 to 140 of about 4,426,359 (306)

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Script P12: Antibiotic Resistance v1

, 2016
This protocol provides a method for analysis of the relative abundance of potential antibiotic resistance genes found in the virome. We use the Comprehensive Antibiotic Resistance Database (CARD) as our reference for potential antibiotic resistance genes.
not provided GRICE EA, not provided ET AL., HANNIGAN GD   +2 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Acquired Bacterial Resistance to Antibiotics and Resistance Genes: From Past to Future

Antibiotics
The discovery, commercialization, and regular administration of antimicrobial agents have revolutionized the therapeutic paradigm, making it possible to treat previously untreatable and fatal infections.
Michela Galgano, Francesco Pellegrini, Elisabetta Catalano, Loredana Capozzi, Laura Del Sambro, Alessio Sposato, Maria Stella Lucente, Violetta Iris Vasinioti, Cristiana Catella, Amienwanlen Eugene Odigie, Maria Tempesta, Annamaria Pratelli, Paolo Capozza   +12 more
doaj   +1 more source

Antibiotic resistance spread in food

, 1997
Nutritive and therapeutic treatment of farm animals with antibiotics, amounting to half of the world's antibiotic output, has selected for resistant bacteria that may contaminate the food produced.
Marianne Boeglin, Michael Teuber, Teuber, Michael, Vincent Perreten, Boeglin, Marianne, Franziska Schwarz, Gottfried Dasen, Cresta, Luana, Perreten, Vincent, Dasen, Gottfried, Luana Cresta, Schwarz, Franziska   +11 more
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Detection rate of tetracycline antibiotic resistance genes.

Detection rate of tetracycline antibiotic resistance genes.
Songmi Kim (131671), Yunseok Oh (3821392), Zixiao Yu (18265099), Ji-Seok Jang (18265102), Kornsorn Srikulnath (640675), Kyudong Han (35824), Qingyang Li (2443405), Ho-Seong Lee (2249785)   +7 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Chloramphenicol-mobilized Bacillus subtilis transiently expresses resistance to multiple antibiotics, including the glycopeptides phleomycin and bleomycin

Journal of Bacteriology
Antibiotic resistance presents an urgent global crisis, exacerbated by antibiotic overuse. Understanding the regulation of resistance genes within bacterial populations can inform strategies to prevent the spread of antibiotic resistance, and reveal how ...
Amelia Brave, Sandra LaBonte, Yongjin Liu, Morgan Powers, Evan De Ford, Paul D. Straight   +5 more
doaj   +1 more source

Drug Resistant Streptococcus pneumoniae (DRSP) in the Maltese Islands [PDF]

, 2004
The DRSP prevalence rate for the Maltese Islands was investigated. Consecutive samples were obtained, both from adults and children, from September 2000 through April 2002.
Micallef, Christianne, Cuschieri, Paul, Barbara, Christopher, Cassar, Robert   +3 more
core