Results 111 to 120 of about 4,426,359 (306)

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

open access: yesAdvanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang   +7 more
wiley   +1 more source

Fate of antibiotic resistant bacteria and genes during wastewater chlorination: implication for antibiotic resistance control.

open access: yesPLoS ONE, 2015
This study investigated fates of nine antibiotic-resistant bacteria as well as two series of antibiotic resistance genes in wastewater treated by various doses of chlorine (0, 15, 30, 60, 150 and 300 mg Cl2 min/L). The results indicated that chlorination
Qing-Bin Yuan, Mei-Ting Guo, Jian Yang
doaj   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

open access: yesAdvanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz   +9 more
wiley   +1 more source

Microbiota as a reservoir of antibiotic resistance genes: relevance and urgency

open access: yesUniversa Medicina
'Antimicrobial resistance' (AMR) is one of the top threats to global public health and developments.
Naga Raju Maddela
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

open access: yesAdvanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Scolopax rusticola Carrying Enterobacterales Harboring Antibiotic Resistance Genes

open access: yes
The Eurasian woodcock (Scolopax rusticola) belongs to those bird species that make systematic migratory flights in spring and autumn in search of favorable breeding and wintering areas.
Francesco La Russa   +10 more
core   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

open access: yesAdvanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye   +11 more
wiley   +1 more source

The potential ecological risk of co and cross-selection resistance between disinfectant and antibiotic in dairy farms

open access: yesEnvironmental Advances
The surge in antibiotic use in various industries has led to increased excretion of antibiotic resistance genes (ARG) to the environment, this poses threat to human and animal health.
Ncumisa Mpongwana   +4 more
doaj   +1 more source

Antibiotic Resistance Genes (ResFinder)

open access: yes
Results of antibiotic resistance genes –assemblies’ screening- using Abricate v0.8 and Resfinder database (downloaded last 5 March 2019).
Silvia García-Cobos (18055450)
core   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani   +2 more
wiley   +1 more source

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