Results 241 to 250 of about 4,426,359 (306)

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Antibiotic resistance genes are more abundant in microplastic textile biofilms than natural cotton biofilms in freshwater. [PDF]

Appl Environ Microbiol
Nguyen NHA, Bohmova A, Novotna J, Wiener J, Riha J, Hoang TC, Sevcu A.   +6 more
europepmc   +1 more source

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

A correlation analysis between arsenic and mercury resistance and the spread of antibiotic resistance genes in bacteria isolated from a highly contaminated brownfield. [PDF]

Front Microbiol
Prosenkov A, Sala Fernández D, Gallego JLR, Peláez AI.   +3 more
europepmc   +1 more source

AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells

Advanced Science, EarlyView.
Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding, Haibiao Xu, Cen Liu, Yangyin Ding, Shuai Wang, Jun Yin, Tao Fu, Xiao Jiang, Yuning Chen, Hui Luo, Rui Li, Zhengxin Chen, Huibo Wang   +12 more
wiley   +1 more source

Comprehensive profiling of antibiotic resistance genes and functional clusters of orthologous groups annotation of gut microbiota in Indonesian Kedu chickens. [PDF]

J Genet Eng Biotechnol
Agusetyaningsih I, Lestari DA, Pandupuspitasari NS, Setiaji A, Philco SV, Sugiharto S.   +5 more
europepmc   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Pathogenic potential of MDR Enterococcus faecalis in tilapia and mullet with insight into virulence traits, antibiotic resistance genes, and multidrug resistance patterns. [PDF]

Sci Rep
Mabrok M, Algammal AM, Mohamed YS, Steele S, Alatawy M, Alenzi AM, Al-Otaibi AS, Almuzaini AM, Mursalim MF, Dayrit GB, Abo Hashem ME.   +10 more
europepmc   +1 more source

The Potential of Self‐Maintainable Living Materials

Advanced Science, EarlyView.
Self‐maintainable living materials are presented as the next generation of bioadaptive systems, integrating continuous sensing, decision‐making, response, self‐repair, and adaptation in a closed‐loop framework. This review highlights the design principles and emerging technologies that enable autonomous, long‐term functionality for future regenerative ...
Mohammadsadegh Nadimifar, Tatiane Eufrásio‐da‐Silva, Lidia Maeso, Gorka Orive, Alireza Dolatshahi‐Pirouz   +4 more
wiley   +1 more source

In Silico Genomic Analysis of Antibiotic Resistance Genes Carried by Mobile Genetic Elements in <i>Pseudomonas aeruginosa</i>. [PDF]

Int J Mol Sci
Liu Y, Han Y.
europepmc   +1 more source