Results 171 to 180 of about 3,260,507 (313)

Uridine and pyruvate supplementation is associated with Th1 polarization during mitotoxic antibiotic therapy. [PDF]

iScience
De Santis S, Rutigliano M, Simone F, Larocca L, Matrella ML, Milella M, Vavallo A, Ditonno P, Marrano N, Mestice A, Battaglia S, Battaglia M, Moschetta A, Seibel P, Piccinin E, Villani G.   +15 more
europepmc   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Duration of antibiotic therapy: with or without biomarkers? [PDF]

Acute Crit Care
Guerreiro GS, Fustiga J, Póvoa P.
europepmc   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Partial Oral Antibiotic Therapy for Infective Endocarditis: A Practical Review of Current Evidence and Guidelines. [PDF]

Pathogens
Roland T, Yombi JC.
europepmc   +1 more source

The Complications of Antibiotic Therapy

International Journal of Clinical Practice, 1956
openaire   +2 more sources

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Efficiency of nanovaccines compared with antibiotic therapy in the prevention and immunomodulation of listeriosis. [PDF]

Emerg Microbes Infect
Alvarez-Dominguez C, Calderón-Gonzalez R, Salcines-Cuevas D, Soriano V, Ubeda M, Montoya N, Calvo-Montes J, Marradi M, Freire J, Gomez-Roman J, Gonzalez-Lopez E, Ocejo-Vinyals JG, Marimon JM, Vazquez E, Moreno-Torres V.   +14 more
europepmc   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Correction: Clinical efficacy of empiric antibiotic therapy in Chinese patients with cirrhosis and bacterial infections: A multicenter study. [PDF]

PLoS One
Sheng L, Zhang X, Weng H, Deng Q, Deng M, Wu X, Huang Z, Liu S, Wu R, Ma C, Xu Y, Zhong J, Yang J, Wu Y, Shen H, Ding F, Wang F, Zhai X, Peng C, Ren H, Jin J, Xu X, Li X, Ye X, Qian G, Sun S, Yao X, Miao H, Xiao Q, Ye S, Zhang Q, Xu X, Xu X, Yu Y, Tu H, Zhang X, Huang R, Yang Q, Sheng J, Shi Y, Yu X.   +40 more
europepmc   +1 more source