Results 91 to 100 of about 867,243 (251)
Advanced Science, EarlyView.Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang +8 more
wiley +1 more source
Bacterial Minicell‐Based Biohybrid Sub‐micron Swimmers for Targeted Cargo Delivery
Advanced Science, EarlyView.Bacterial minicells, vesicles derived from engineered E. coli, offer promising sub‐micron scale biohybrid swimmers for targeted cargo delivery. Purified with over 99% efficiency while retaining motility, they are functionalized with MNPs for controlled movement.
Saadet Fatma Baltaci +4 more
wiley +1 more source
Advanced Science, EarlyView.Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra +9 more
wiley +1 more source
Advanced Science, EarlyView.A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni +6 more
wiley +1 more source
Antimicrobial Agents and Chemotherapy, 1979 J. Jacobs, J. Michel, T. Sacks
semanticscholar +1 more source
Antimicrobial Agents and Chemotherapy, 1979 J. Michel, J. Jacobs, T. Sacks
semanticscholar +1 more source
Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation
Advanced Science, EarlyView.PANoptosis activation is an effective therapeutic target during mastitis progression, and Gasdermin D activation is key factor contributing to blood milk barrier damage during mastitis, while cyanidin 3‐O‐galactoside can inhibit these targets to exert a protective effect. Therefore, the extraction of key active ingredients from plants for the treatment
Rui Feng +23 more
wiley +1 more source
When a Safety Signal Appears: Do the Right Thing
Frontiers in Public Health, 2013 John Franklyn Riefler
doaj +1 more source
Recent Developments in Nanoparticle‐Hydrogel Hybrid Materials for Controlled Release
Advanced Science, EarlyView.This review highlights recent advances in nanoparticle–hydrogel hybrid materials for controlled drug delivery. It explores diverse nanocarrier–hydrogel combinations, drug loading strategies, release mechanisms, and stimuli‐responsive behaviors. Emphasis is placed on the molecular interactions driving hybrid material performance, offering insights into ...
Yiping Fan +8 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim +7 more
wiley +1 more source