Results 121 to 130 of about 2,598,203 (404)

Medication Use in Multiple Sclerosis: A Population‐Based Comparison With the General Danish Population

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen, Henrik Horwitz, Ida M. Heerfordt, Elisabeth Framke, Melinda Magyari   +4 more
wiley   +1 more source

Study of Antibacterial Activity and Energy of Formation of Peptide Ligand Complexes With Hybrid Antibiotics Vancomycin-Azithromycin and Eremomycin-Azithromycin

Антибиотики и Химиотерапия, 2020
Antibacterial activity of hybrid antibiotics vancomycin-azithromycin (C11, C12-carbonate) and eremomycin-azitromycin (C11, C12-carbonate) was evaluated. Quantum chemical calculations of complexes of hybrid antibiotics with a model tripeptide ligand a, ε ...
E. E. Bykov, E. P. Mirchink, E. B. Isakova, E. N. Bychkova, E. N. Olsufyeva, A. N. Tevyashova   +5 more
doaj  

Agreement of Administrative Pharmacy Dispensing With Self‐Reported Use of Oral Prednisone in US Veterans With Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Administrative claims are used to evaluate oral glucocorticoid use in rheumatoid arthritis (RA), despite limited evidence to support accuracy. We aimed to evaluate the performance of claims‐based algorithms for glucocorticoid use compared to self‐report in an RA population.
Beth I. Wallace, Bryant R. England, Joshua F. Baker, Michael D. George, Brian C. Sauer, Jorge Rojas, Punyasha Roul, Katherine D. Wysham, Hannah Brubeck, Isaac Smith, Liron Caplan, Paul A. Monach, Gail S. Kerr, Gary Kunkel, Tawnie Braaten, Ted R. Mikuls, Grant W. Cannon   +16 more
wiley   +1 more source

The Effectiveness of the Combined Use of Meropenem and Avibactam Against Carbapenemase-Producing Klebsiella pneumoniae Strains in an in vitro Dynamic Model

Антибиотики и Химиотерапия
Background. Combinations of carbapenems with new-generation carbapenemase inhibitors are successfully used to combat infections caused by carbapenemase-producing Klebsiella pneumoniae strains. However, K.
E. N. Strukova, M. V. Golikova, M. B. Kobrin, S. A. Dovzhenko, A. V. Golyshkin, N. R. Almyasheva, Yu. A. Portnoy   +6 more
doaj   +1 more source

Effect of β-lactamase inhibitors on in vitro activity of β-lactam antibiotics against Burkholderia cepacia complex species [PDF]

, 2016
Background: Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients. Intrinsic resistance to a wide range of antimicrobial agents, including a variety of beta-
Coenye, Tom, Everaert, Annelien
core   +2 more sources

Action and resistance mechanisms of antibiotics: A guide for clinicians

Journal of Anaesthesiology Clinical Pharmacology, 2017
Infections account for a major cause of death throughout the developing world. This is mainly due to the emergence of newer infectious agents and more specifically due to the appearance of antimicrobial resistance.
Garima Kapoor, S. Saigal, Ashok Elongavan   +2 more
semanticscholar   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

ANTIBACTERIAL PROPERTIES OF AMICOUMYCIN A

Антибиотики и Химиотерапия, 2020
The in vitro activity of the antibiotic amikumacin A against 22 collective test strains and 24 clinical isolates of bacteria and fungi was studied. It is shown that amicoumycin A has a broad antimicrobial spectrum of activity.
O. V. Efremenkova, N. I. Gabrielyan, I. A. Malanicheva, T. A. Efimenko, I. G. Sumarukova, A. A. Gluhova, YU. V. Boykova, E. A. Rogozhin, A. M. Korolev, V. A. Korshun, I. V. Drabkina   +10 more
doaj  

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

Antioxidant Properties of Water-Soluble Polysaccharides and Ethanolic Extracts of Xylotrophic Basidiomycetes Mycelium

Антибиотики и Химиотерапия, 2020
The present study was conducted to investigate the antioxidant properties of water-soluble polysaccharides and ethanolic extracts of submerged mycelium of basidiomycetes Ganoderma lucidum (Curtis) P.
N. R. Almyasheva, M. S. Yarina, A. V. Golyshkin, B. R. Dzhavakhyan, L. M. Krasnopolskaya   +4 more
doaj