Results 131 to 140 of about 2,694,182 (391)

Fitness Costs of Antibiotic Resistance Impede the Evolution of Resistance to Other Antibiotics [PDF]

, 2023
Farhan Rahman Chowdhury, Brandon Findlay
openalex   +1 more source

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source

Design of Novel Carboxamides of Eremomycin and Vancomycin with 4- or 3-Amino Methyl Phenyl Boric Acid and Their Investigation

Антибиотики и Химиотерапия, 2020
Amidation of the end carboxyl group of eremomycin and vancomycin by pinacolinic 4- or 3-amino methyl phenyl boron acids esters in the presence of the condensing reagent PyBOP resulted in formation of novel carboxamides of the antibiotics (IIIa-VIa ...
E. N. Bychkova, A. M. Korolev, E. N. Olsufyeva, E. P. Mirchink, E. B. Isakova   +4 more
doaj  

Persistent and susceptible bacteria with individual deaths

, 2013
The aim of this paper is to study two models for a bacterial population subject to antibiotic treatments. It is known that some bacteria are sensitive to antibiotics.
Zucca, Fabio
core   +1 more source

Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study [PDF]

, 2020
Heng Fan, Ruth Gilbert, Finbar O’Callaghan, Leah Li   +3 more
openalex   +1 more source

Are antibiotics naturally antibiotics?

Journal of Industrial Microbiology & Biotechnology, 2006
Antibiotics have been used for more than 50 years and are the cornerstone of infectious disease treatment; in addition, these low-molecular-weight bioactive compounds have been applied to many other therapeutic purposes. However, there is almost no information on the evolutionary biology or ecology of naturally occurring low-molecular-weight compounds.
openaire   +2 more sources

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Antimicrobial resistance profile of clinical isolates from hospitals across China: CHINET 2024 surveillance report

One Health Advances
This study aimed to monitor clinical isolate susceptibility to antimicrobial agents in healthcare facilities in 31 provinces or cities of China in 2024.
Yan Guo, Li Ding, Renru Han, Dandan Yin, Shi Wu, Yang Yang, Fu Wang, Demei Zhu, Fupin Hu, the China Antimicrobial Surveillance Network (CHINET) Study Group   +9 more
doaj   +1 more source

Prediction of Aztreonam Effectiveness Against Klebsiella pneumoniae Based on the Results of Antimicrobial Susceptibility Testing with Increased Inoculum

Антибиотики и Химиотерапия
Background. The minimum inhibitory concentration (MIC) does not predict the risk of antibacterial resistance development due to a small sample of tested bacteria.
K. N. Alieva, M. V. Golikova, D. A. Kondratieva, A. A. Kuznetsova   +3 more
doaj   +1 more source

Diastereoselective Synthesis of Spirocyclopropanes under Mild Conditions via Formal [2 + 1] Cycloadditions Using 2,3-Dioxo-4-benzylidene-pyrrolidines

Molecules, 2017
A highly diastereoselective cyclopropanation of cyclic enones with sulfur ylides was developed under catalyst-free conditions, producing multifunctional spirocyclopropanes in generally excellent yields (up to 99% yield and >99:1 d.r.).
Yi Li, Qing-Zhu Li, Li Huang, Hong Liang, Kai-Chuan Yang, Hai-Jun Leng, Yue Liu, Xu-Dong Shen, Xiao-Jun Gou, Jun-Long Li   +9 more
doaj   +1 more source