Results 61 to 70 of about 1,877,361 (339)

Evaluation of the Immunochromatographic NG-Test Carba 5, RESIST-5 O.O.K.N.V., and IMP K-SeT for Rapid Detection of KPC-, NDM-, IMP-, VIM-type, and OXA-48-like Carbapenemase Among Enterobacterales

Frontiers in Microbiology, 2021
BackgroundEnterobacterales are the most common pathogens for nosocomial infections. The emergence and spread of KPC, NDM, and OXA-48-like carbapenemase-producing Enterobacterales with their extensively drug-resistant characteristics have posed great ...
Renru Han, Renru Han, Yan Guo, Yan Guo, Mingjia Peng, Mingjia Peng, Qingyu Shi, Qingyu Shi, Shi Wu, Shi Wu, Yang Yang, Yang Yang, Yonggui Zheng, Yonggui Zheng, Dandan Yin, Dandan Yin, Fupin Hu, Fupin Hu   +17 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Antimicrobial Properties of Eremoxylarin A Produced by Ascomycete of Sordariomycetes in Submerged Culture

Антибиотики и Химиотерапия, 2020
The fungal strain INA 01108 producing antibiotic substances with broad spectrum of antibacterial activity was isolated from the natural environment.
O. V. Efremenkova, B. F. Vasiljeva, V. A. Zenkova, A. M. Korolev, Y. N. Lusikov, T. A. Efimenko, I. A. Malanicheva, E. P. Mirchink, E. B. Isakova, E. N. Bilanenko, O. V. Kamzolkina   +10 more
doaj  

Development of a risk prediction model for bloodstream infection in patients with fever of unknown origin

Journal of Translational Medicine, 2022
Background Bloodstream infection (BSI) is a significant cause of mortality among patients with fever of unknown origin (FUO). Inappropriate empiric antimicrobial therapy increases difficulty in BSI diagnosis and treatment.
Teng Xu, Shi Wu, Jingwen Li, Li Wang, Haihui Huang   +4 more
doaj   +1 more source

Antibiotic residues and antibiotic-resistant bacteria in pig slurry used to fertilize agricultural fields [PDF]

, 2020
Pig manure may contain antibiotic residues, antibiotic-resistant bacteria or pathogens, which may reach the environment upon fertilization. During this study, 69 antibiotic residues belonging to 12 classes were quantified in 89 pig slurry samples.
Colson, Lander, Daeseleire, Els, De Carvalho Ferreira, Helena Cardoso, Decrop, Johan, Dewulf, Jeroen, Herman, Lieve, Heyndrickx, Marc, Meirlaen, Jurgen, Rasschaert, Geertrui, Van Elst, Daan   +9 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

COMPOUNDS BASED ON TRIS(1-ALKYLINDOL-3-YL)METHAN FOR OVERCOMING DRUG RESISTANCE IN PATHOGENS

Антибиотики и Химиотерапия, 2020
Trls(1-alkylindol-3-yl)methylium salts that are trls(1-alkylindol-3-yl)methan derivatives with high antibacterial and antifungal activity were obtained through chemical synthesis.
A. S. Trenin, S. N. Lavrenov, E. P. Mirchink, E. B. Isakova, O. P. Bychkova, A. Y. Simonov, S. A. Lakatosh, E. A. Tsvigun   +7 more
doaj  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Optimization of the Nutrient Medium for Flammulina velutipes Submerged Biomass Production and Micromorphology of Its Mycelium

Fermentation, 2021
Based on the assessment of the trophic needs of basidiomycete Flammulina velutipes and the optimization of the composition of the nutrient medium using design of experimental approach, the yield of the submerged biomass of the fungus was increased to 41 ...
Larissa Krasnopolskaya, Maria Shuktueva, Aleksandr Golyshkin, Nailya Almyasheva, Maria Yarina   +4 more
doaj   +1 more source

Determination of antimicrobial susceptibilities on infected urines without isolation [PDF]

, 1979
A method is described for the quick determination of the susceptibilities of various unidentified bacteria contained in an aqueous physiological fluid sample, particularly urine, to one or more antibiotics.
Barza, M. J., Chappelle, E. W., Deming, J. W., Picciolo, G. L., Shrock, C. G., Vellend, H., Weinstein, L.   +6 more
core   +1 more source