Results 81 to 90 of about 1,625,451 (291)

Study of Antibacterial Activity and Energy of Formation of Peptide Ligand Complexes With Hybrid Antibiotics Vancomycin-Azithromycin and Eremomycin-Azithromycin

Антибиотики и Химиотерапия, 2020
Antibacterial activity of hybrid antibiotics vancomycin-azithromycin (C11, C12-carbonate) and eremomycin-azitromycin (C11, C12-carbonate) was evaluated. Quantum chemical calculations of complexes of hybrid antibiotics with a model tripeptide ligand a, ε ...
E. E. Bykov, E. P. Mirchink, E. B. Isakova, E. N. Bychkova, E. N. Olsufyeva, A. N. Tevyashova   +5 more
doaj  

Microbial diversity in individuals and their household contacts following typical antibiotic courses. [PDF]

, 2016
BackgroundAntibiotics are a mainstay of treatment for bacterial infections worldwide, yet the effects of typical antibiotic prescriptions on human indigenous microbiota have not been thoroughly evaluated.
Abeles, Shira R, Jones, Marcus B, Klitgord, Niels, Ly, Melissa, Nelson, Karen E, Pride, David T, Santiago-Rodriguez, Tasha M, Yooseph, Shibu   +7 more
core   +2 more sources

Characterization of Antibiotic and Biocide Resistance Genes and Virulence Factors of Staphylococcus Species Associated with Bovine Mastitis in Rwanda [PDF]

, 2020
The present study was conducted from July to August 2018 on milk samples taken at dairy farms in the Northern Province and Kigali District of Rwanda in order to identify Staphylococcus spp. associated with bovine intramammary infection.
Antók, Fruzsina Irén, Ehling-Schulz, Monika, Ehricht, Ralf, Feßler, Andrea T., Fischer, Otto, Grunert, Tom, Keinprecht, Helga, Lepuschitz, Sarah, Loncaric, Igor, Marbach, Helene, Masengesho, Jean Claude, Mayrhofer, Rosa, Monecke, Stefan, Nyirimbuga, Vedaste, Ruppitsch, Werner, Schwarz, Stefan, Spergser, Joachim   +16 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The Effectiveness of the Combined Use of Meropenem and Avibactam Against Carbapenemase-Producing Klebsiella pneumoniae Strains in an in vitro Dynamic Model

Антибиотики и Химиотерапия
Background. Combinations of carbapenems with new-generation carbapenemase inhibitors are successfully used to combat infections caused by carbapenemase-producing Klebsiella pneumoniae strains. However, K.
E. N. Strukova, M. V. Golikova, M. B. Kobrin, S. A. Dovzhenko, A. V. Golyshkin, N. R. Almyasheva, Yu. A. Portnoy   +6 more
doaj   +1 more source

Ascorbigen — Rifabutin Toxicity Modifier

Антибиотики и Химиотерапия, 2020
Relevance. Indications for rifabutin use are constantly expanding. It is used in the treatment of extremely complex nosological forms of infectious diseases. However, side effects of the medication, such as gastrointestinal toxicity and myelosuppression,
E. R. Pereverzeva, M. I. Treshchalin, I. D. Treshchalin   +2 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

ANTIBACTERIAL PROPERTIES OF AMICOUMYCIN A

Антибиотики и Химиотерапия, 2020
The in vitro activity of the antibiotic amikumacin A against 22 collective test strains and 24 clinical isolates of bacteria and fungi was studied. It is shown that amicoumycin A has a broad antimicrobial spectrum of activity.
O. V. Efremenkova, N. I. Gabrielyan, I. A. Malanicheva, T. A. Efimenko, I. G. Sumarukova, A. A. Gluhova, YU. V. Boykova, E. A. Rogozhin, A. M. Korolev, V. A. Korshun, I. V. Drabkina   +10 more
doaj  

Prescribing antibiotics to preschool children in primary health care in Croatia [PDF]

, 2008
The use of antibiotics depends on cultural and socioeconomic factors, physician's characteristics as well as on microbiological considerations. Aim of our study was to asses antibiotic prescription among preschool children in primary health care in ...
Bergman-Marković, Biserka, Blažeković-Milaković, Sanja, Matijašević, Ivana, Stojanović-Špehar, Stanislava, Vrca-Botica, Marija   +4 more
core