Results 91 to 100 of about 1,145,667 (304)

Antimicrobial resistance profile of clinical isolates from hospitals across China: CHINET 2024 surveillance report

One Health Advances
This study aimed to monitor clinical isolate susceptibility to antimicrobial agents in healthcare facilities in 31 provinces or cities of China in 2024.
Yan Guo, Li Ding, Renru Han, Dandan Yin, Shi Wu, Yang Yang, Fu Wang, Demei Zhu, Fupin Hu, the China Antimicrobial Surveillance Network (CHINET) Study Group   +9 more
doaj   +1 more source

Diastereoselective Synthesis of Spirocyclopropanes under Mild Conditions via Formal [2 + 1] Cycloadditions Using 2,3-Dioxo-4-benzylidene-pyrrolidines

Molecules, 2017
A highly diastereoselective cyclopropanation of cyclic enones with sulfur ylides was developed under catalyst-free conditions, producing multifunctional spirocyclopropanes in generally excellent yields (up to 99% yield and >99:1 d.r.).
Yi Li, Qing-Zhu Li, Li Huang, Hong Liang, Kai-Chuan Yang, Hai-Jun Leng, Yue Liu, Xu-Dong Shen, Xiao-Jun Gou, Jun-Long Li   +9 more
doaj   +1 more source

Characteristics of demand for antibiotics in primary care: an almost ideal demand system approach [PDF]

We model demand for different classes of antibiotics used for respiratory infections in outpatient care using a linear approximate almost ideal demand system approach.
Karine Moschetti, Massimo Filippini, Giuliano Masiero   +2 more
core   +1 more source

The binding of antibiotics to ERp57/GRP58

, 2008
The effects of five antibiotics, previously described as ligands of protein disulfide isomerase PDI, have now been studied on the homologous protein ERp57.
EUFEMI, Margherita, TURANO, Carlo, Margherita Eufemi, GRILLO, CATERINA, E. Del Vecchio, CHICHIARELLI, Silvia, Elisa Gaucci, Emiliana Del Vecchio, Silvia Chichiarelli, Carlo Turano, Caterina Grillo   +10 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

ANTIBIOTIC RESISTANCE

Critical Care Clinics, 1998
Antibiotic resistance is an increasing problem in many parts of the world. Antibiotic resistance has been associated with the use of some antibiotics but not with others. Due to the overuse of antibiotics with a high resistance potential, there has been an increase of resistance with certain bacteria, e.g., Staphylococcus aureus, Pseudomonas aeruginosa
openaire   +3 more sources

"Practical Knowledge" and Perceptions of Antibiotics and Antibiotic Resistance Among Drugsellers in Tanzanian Private Drugstores. [PDF]

, 2010
Studies indicate that antibiotics are sold against regulation and without prescription in private drugstores in rural Tanzania. The objective of the study was to explore and describe antibiotics sale and dispensing practices and link it to drugseller ...
Mujinja, Phare, Tomson, G., Göran Tomson, Tomson, Göran, Kalala, W., Viberg, Nina, Kalala, Willbrord, Viberg, N., Lundborg Cecilia, Cecilia Stålsby Lundborg, Willbrord Kalala, Lundborg, Cecilia Stålsby, Mujinja, P., Lundborg, C.S., Phare Mujinja, Nina Viberg, Mujinja Phare, Viberg Nina, Tomson Göran, Kalala Willbrord   +19 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Clinical characteristics and antimicrobial therapy of healthcare-associated carbapenem-non-susceptible gram-negative bacterial meningitis: a 16-year retrospective cohort study

BMC Infectious Diseases
Objective Healthcare-associated Gram-negative bacterial meningitis is a substantial clinical issue with poor outcomes, especially for neurosurgical patients.
Jiyan Xu, Xiaoling Du, Dan Li, Pei Li, Qinglan Guo, Xiaogang Xu, Fupin Hu, Minggui Wang   +7 more
doaj   +1 more source

PK/PD Modeling as a Tool for Predicting Bacterial Resistance to Antibiotics: Alternative Analyses of Experimental Data

Антибиотики и Химиотерапия, 2020
Postexposure number of mutants (NM) is a conventional endpoint in bacterial resistance studies using in vitro dynamic models that simulate antibiotic pharmacokinetics.
M. V. Golikova, E. N. Strukova, Y. A. Portnoy, A. A. Firsov   +3 more
doaj