Monoclonal antibodies and bacterial virulence [PDF]
Virulence, 2017 This issue of Virulence features an article entitled “Antibodies to Staphylococcus aureus capsular polysaccharides 5 and 8 perform similarly in vitro but are functionally distinct in vivo”1 which d...
Luigi Iannetti, Mirella Luciani
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Inhibition of Bacterial Superantigens by Peptides and Antibodies [PDF]
Infection and Immunity, 2001 ABSTRACTThe pyrogenic exotoxins of group A streptococci and staphylococcal enterotoxins are a family of structurally related superantigens with similar biological activity. Two distinct areas have been identified which have a highly conserved amino acid homology in all of the toxin families.
Pavel Pugach +6 more
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The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling [PDF]
, 2014 Chlamydia trachomatis, the causative agent of trachoma and sexually transmitted infections, employs a type III secretion (T3S) system to deliver effector proteins into host epithelial cells to establish a replicative vacuole.
Bastidas, Robert J. +6 more
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Specificity of secretory antibodies to bacterial immunogens [PDF]
Infection and Immunity, 1976 The present investigation examined the specificity of the salivary immune response of axenic and conventional mice to topically administered Salmonella typhi, S. gallinarum, and S. typhimurium. Specific antibacterial antibodies were determined by passive hemagglutination and bacterial agglutination. Reciprocal antibody titers up to 320 were detected in
J A Molinari, J L Ebersole
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TIV vaccination modulates host responses to influenza virus infection that correlate with protection against bacterial superinfection [PDF]
, 2019 Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or the
Choi, Angela +4 more
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Isolation of recombinant antibodies directed against surface proteins of Clostridium difficile [PDF]
, 2016 Clostridium difficile has emerged as an increasingly important nosocomial pathogen and the prime causative agent of antibiotic-associated diarrhoea and pseudomembranous colitis in humans.
Aitken, Robert, Shirvan, Ali Nazari
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Antibodies against bacterial membrane proteins [PDF]
Journal of Endotoxin Research, 1999 Prior studies have shown that antiserum raised to the Escherichia coli J5 vaccine binds to three bacterial outer membrane proteins (OMPs) that are present on serum-exposed smooth Enterobacteriaceae and in LPS-containing fragments that are released by bacteria incubated in human serum.
H. Shaw Warren, Judith Hellman
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Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]
, 1991 " An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
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Characterization of egg yolk immunoglobulin (IgY) against enterotoxigenic Escherichia coli and evaluation of its effects on bovine intestinal cells [PDF]
, 2013 Escherichia coli (ETEC) infection is common in calves. Egg yolk antibodies (IgY) have been used to treat gastrointestinal infectious diseases. This study aimed to characterize IgY against bovine ETEC and to evaluate its effects on bovine intestinal cell ...
Alustiza, Fabrisio Eduardo +7 more
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Disease-Enhancing Antibodies Improve the Efficacy of Bacterial Toxin-Neutralizing Antibodies [PDF]
Cell Host & Microbe, 2013 During infection, humoral immunity produces a polyclonal response with various immunoglobulins recognizing different epitopes within the microbe or toxin. Despite this diverse response, the biological activity of an antibody (Ab) is usually assessed by the action of a monoclonal population.
Mary Ann Pohl +5 more
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