Results 11 to 20 of about 3,053,812 (327)
Monoclonal Antibodies as an Antibacterial Approach Against Bacterial Pathogens
Antibiotics, 2020 In the beginning of the 21st century, the frequency of antimicrobial resistance (AMR) has reached an apex, where even 4th and 5th generation antibiotics are becoming useless in clinical settings.
Daniel V. Zurawski, Molly K. McLendon
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Antibodies, 2018 Antibiotic-resistant bacterial pathogens are increasingly implicated in hospital- and community-acquired infections. Recent advances in monoclonal antibody (mAb) production and engineering have led to renewed interest in the development of antibody-based
Shun Xin Wang-Lin, Joseph P. Balthasar
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Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity [PDF]
Nature Communications, 2017 Antibodies against the platelet factor 4 (PF4) support bacterial host defence but in some cases may lead to heparin-induced thrombocytopenia (HIT).
Thi-Huong Nguyen +3 more
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Immunoglobulin for Treating Bacterial Infections: One More Mechanism of Action
Antibodies, 2019 The mechanisms underlying the effects of immunoglobulins on bacterial infections are thought to involve bacterial cell lysis via complement activation, phagocytosis via bacterial opsonization, toxin neutralization, and antibody-dependent cell-mediated ...
Teiji Sawa +4 more
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Antibodies directed against bacterial antigens in sera of Polish patients with primary biliary cholangitis [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundPrimary biliary cholangitis (PBC) is a cholestatic, autoimmune liver disease with the presence of characteristic autoantibodies. The aim of the work was to determine the level of antibodies directed against bacterial antigens: Chlamydia ...
Alicja Bauer, Andrzej Habior
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Monoclonal antibody-based therapies for bacterial infections [PDF]
Current Opinion in Infectious Diseases, 2019 Purpose of review This review highlights recent developments in the development of monoclonal antibodies to treat bacterial disease, including preclinical advances and the status of current clinical trials. Recent findings Monoclonal antibody (mAb) therapy is becoming increasingly ...
Bettina C. Fries +2 more
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Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow [PDF]
Nature CommunicationsThis study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples.
Alejandro Gomez Toledo +13 more
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Natural Catalytic Antibodies in Norm, Autoimmune, Viral, and Bacterial Diseases
The Scientific World Journal, 2010 In human patients with autoimmune, viral, and bacterial diseases, the generation of antibodies (Abs) to foreign antigens and/or autoantibodies to self-antigens usually occurs.
Georgy A. Nevinsky, Valentina N. Buneva
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Frontiers in Immunology, 2023 Antibody-dependent enhancement (ADE) of bacterial infections occurs when blocking or inhibitory antibodies facilitate the infectivity of pathogens. In humans, antibodies involved in ADE of bacterial infections may include those naturally produced against
Sara Olivera-Ardid +14 more
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Increased levels of IgG antibodies against human HSP60 in patients with spondyloarthritis. [PDF]
PLoS ONE, 2013 Spondyloarthritis (SpA) comprises a heterogeneous group of inflammatory diseases, with strong association to human leukocyte antigen (HLA)-B27. A triggering bacterial infection has been considered as the cause of SpA, and bacterial heat shock protein ...
Astrid Hjelholt +6 more
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