Glycobiology, 2020 Abundant evidence points to a critical role for antibodies in protection and pathology across infectious diseases. While the antibody variable domain facilitates antibody binding and the blockade of infection, the constant domain (Fc) mediates cross talk
Edward B. Irvine, G. Alter
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Gold nanoparticles for preparation of antibodies and vaccines against infectious diseases
Expert Review of Vaccines, 2020 Introduction Vaccination remains very effective in stimulating protective immune responses against infections. An important task in antibody and vaccine preparation is to choose an optimal carrier that will ensure a high immune response.
L. Dykman
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Clinical and Developmental Immunology, 2008 We previously demonstrated that purified polyclonal and monoclonal anti-dsDNA antibodies bind a 15-mer peptide ASPVTARVLWKASHV in ELISA and Dot blot. This 15-mer peptide partial sequence ARVLWKASH shares similarity with burkholderia bacterial cytochrome ...
Wei Zhang, Morris Reichlin
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Lifestyle, dietary factors and antibody levels to oral bacteria in cancer-free participants of a European cohort study [PDF]
, 2013 Background—Increasing evidence suggests that oral microbiota play a pivotal role in chronic diseases, in addition to the well-established role in periodontal disease.
Barricarte, Aurelio +43 more
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Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection
Science, 2019 Phage subverts immune response Pseudomonas aeruginosa (Pa) is a multidrug-resistant Gramnegative bacterium commonly found in health care settings. Pa infections frequently result in considerable morbidity and mortality. Sweere et al. found that a type of
J. Sweere +20 more
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Emergence and significance of carbohydrate-specific antibodies
Genes and Immunity, 2020 Carbohydrate-specific antibodies are widespread among all classes of immunoglobulins. Despite their broad occurrence, little is known about their formation and biological significance.
Katharina Kappler, T. Hennet
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Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth [PDF]
, 2012 Co-infections alter the host immune response but how the systemic and local processes at the site of infection interact is still unclear. The majority of studies on co-infections concentrate on one of the infecting species, an immune function or group of
A Graham +69 more
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Novel antibody assessment method for microbial compositional alteration in the oral cavity
Biochemistry and Biophysics Reports, 2022 Recently, it has been demonstrated that dysbiosis, an alteration in commensal microflora composition, is intimately involved in the onset of a variety of diseases.
Sumire Hoashi-Takiguchi +8 more
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Active invasion of Porphyromonas gingivalis and infection-induced complement activation in ApoE-/- mice brains [PDF]
, 2014 Periodontal disease is a polymicrobial inflammatory disease that leads to chronic systemic inflammation and direct infiltration of bacteria/bacterial components, which may contribute to the development of Alzheimer’s disease.
Chukkapalli, Sasanka +6 more
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Diverse Mechanisms of Protective Anti-Pneumococcal Antibodies
Frontiers in Cellular and Infection Microbiology, 2022 The gram-positive bacterium Streptococcus pneumoniae is a leading cause of pneumonia, otitis media, septicemia, and meningitis in children and adults. Current prevention and treatment efforts are primarily pneumococcal conjugate vaccines that target the ...
Aaron D. Gingerich +3 more
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