Results 31 to 40 of about 366,746 (246)

Continuous-Flow Separation and Efficient Concentration of Foodborne Bacteria from Large Volume Using Nickel Nanowire Bridge in Microfluidic Chip

open access: yesMicromachines, 2019
Separation and concentration of target bacteria has become essential to sensitive and accurate detection of foodborne bacteria to ensure food safety. In this study, we developed a bacterial separation system for continuous-flow separation and efficient ...
Xiaoting Huo   +7 more
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Detection of Bacterial Pathogens by Phage Antibody Display

open access: yesDisease Markers, 2000
Vibrio parahaemolyticus is a halophilic Gramnegative facultative anaerobe commonly found in estuarine waters and in seafood like shellfish. It has been implicated in outbreaks of gastro-enteritis in several countries [1]. Food borne illness caused by V.
Namrata Pai   +3 more
openaire   +3 more sources

Human antibody repertoire frequently includes antibodies to a bacterial biofilm associated protein.

open access: yesPLoS ONE, 2019
We have previously described a native human monoclonal antibody, TRL1068, that disrupts bacterial biofilms by extracting from the biofilm matrix key scaffolding proteins in the DNABII family, which are present in both gram positive and gram negative ...
Stefan Ryser   +3 more
doaj   +1 more source

TIV Vaccination Modulates Host Responses to Influenza Virus Infection that Correlate with Protection against Bacterial Superinfection

open access: yesVaccines, 2019
Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or the
Angela Choi   +4 more
doaj   +1 more source

Functional assays to screen and select monoclonal antibodies that target Yersinia pestis

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Yersinia pestis is a gram-negative bacterium that causes plague in animals and humans. Depending on the route of disease transmission, the bacterium can cause an acute, often fatal disease that has a narrow window for treatment with antibiotics ...
Sergei S. Biryukov   +14 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Recent Developments in Antibody-Based Assays for the Detection of Bacterial Toxins

open access: yesToxins, 2014
Considering the urgent demand for rapid and accurate determination of bacterial toxins and the recent promising developments in nanotechnology and microfluidics, this review summarizes new achievements of the past five years.
Kui Zhu   +4 more
doaj   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

open access: yesFEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling   +4 more
wiley   +1 more source

Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity

open access: yesNature Communications, 2017
Antibodies against the platelet factor 4 (PF4) support bacterial host defence but in some cases may lead to heparin-induced thrombocytopenia (HIT).
Thi-Huong Nguyen   +3 more
doaj   +1 more source

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