Results 51 to 60 of about 3,053,812 (327)

Predicted serotype-specific effectiveness of pneumococcal conjugate vaccines V114 and PCV20 against invasive pneumococcal disease in children

Expert Review of Vaccines
Background Next-generation, higher-valency pneumococcal conjugate vaccines (PCVs), 15-valent PCV V114 and 20-valent PCV (PCV20), have been assessed by comparing their immune responses across serotypes shared with the 13-valent PCV (PCV13).
Josiah Ryman, Jeffrey R. Sachs, Ka Lai Yee, Natalie Banniettis, Jessica Weaver, Thomas Weiss   +5 more
doaj   +1 more source

An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies

Scientific Reports, 2020
Broadly-neutralizing monoclonal antibodies are of high therapeutic utility against infectious diseases caused by bacteria and viruses, as well as different types of intoxications.
Shirin Ahmadi, M. B. Pucca, J. Jürgensen, Rahel Janke, Line Ledsgaard, E. Schoof, Christoffer V. Sørensen, F. Çalışkan, A. H. Laustsen   +8 more
semanticscholar   +1 more source

Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]

, 2017
Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita, Di Mattia, G., Fedele, Giorgio, Frassanito, A., Gesualdo, Francesco, Leone, Pasqualina, Marcellini, Valentina, Midulla, Fabio, Mortari, Eva Piano, Nenna, R., Pandolfi, Elisabetta, Stefanelli, Paola, The Pertussis Study, Gropu, Tozzi, Alberto Eugenio   +13 more
core   +1 more source

Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction in Staphylococcus aureus-induced arthritis [PDF]

, 2018
Background: Staphylococcus aureus-induced arthritis causes rapid joint destruction, often leading to disabling joint damage despite antibiotics. We have previously shown that IL-15 inhibition without antibiotics is beneficial in S.
Bergmann, Berglind, Gjertsson, Inger, Henning, Petra, Jirholt, Pernilla, Lerner, Ulf H., Lindholm, Catharina, McInnes, Iain B., Ohlsson, Claes   +7 more
core   +1 more source

Polyclonal antibodies inhibit growth of key cellulolytic rumen bacterial species

Frontiers in Microbiology, 2023
Antibodies targeting specific bacterial species could allow for modification of the rumen microbial population to enhance rumen fermentation. However, there is limited knowledge of targeted antibody effects on rumen bacteria. Therefore, our objective was
Sara M. Tondini, Roderick I. Mackie, Roderick I. Mackie, Joshua C. McCann   +3 more
doaj   +1 more source

Microtubules in Bacteria: Ancient Tubulins Build a Five-Protofilament Homolog of the Eukaryotic Cytoskeleton [PDF]

, 2011
Microtubules play crucial roles in cytokinesis, transport, and motility, and are therefore superb targets for anti-cancer drugs. All tubulins evolved from a common ancestor they share with the distantly related bacterial cell division protein FtsZ, but ...
A Briegel, A Marchler-Bauer, A. J Koster, A. J Martin-Galiano, Alasdair W. McDowall, B Miroux, C Jenkins, C Suloway, C. A Sontag, C. A Sontag, C. H Aylett, C. V Iancu, D Bermudes, D Nicastro, D Schlieper, D. N Mastronarde, D. N Mastronarde, D. P Devos, E Nogales, E Nogales, E Nogales, E Nogales, E. F Pettersen, E. G Reynaud, E. I Tocheva, F Amat, Giulio Petroni, Grant J. Jensen, H Erickson, H Sui, H. P Erickson, J Cope, J Lowe, J. B Heymann, J. D Thompson, J. D Wisotzkey, J. O McInerney, J. R McIntosh, K. C Lee, K. S Makarova, K. T Tokuyasu, K. T Tokuyasu, L Gan, L Ni, L. A Amos, L. A Amos, Linda Amos, M Pilhofer, M Pilhofer, M Pilhofer, M Takeda, M Wagner, M. S Ladinsky, M. S Ladinsky, Mark S. Ladinsky, Martin Pilhofer, P Forterre, P. J Keeling, R. I Koning, S Vaughan, S. K Dutcher, S. Q Zheng, T Muller, T. K Attwood, W Ludwig, W. F Tivol, Z Li   +66 more
core   +5 more sources

Elevated systemic antibodies towards commensal gut microbiota in autoinflammatory condition [PDF]

, 2008
Article No.
Aminov, Rustam I, Arakelova, Karine A, Ghazaryan, Karine A, Grant, George, Kelly, Denise, Khachatryan, Zaruhi A, Ktsoyan, Zhanna A, Manukyan, Gayane P   +7 more
core   +8 more sources

Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. [PDF]

, 2018
Typhoid fever caused by Salmonella enterica serovar (S.) Typhi differs in its clinical presentation from gastroenteritis caused by S. Typhimurium and other non-typhoidal Salmonella serovars.
Bäumler, Andreas J, Cobb, Brian A, Hiyoshi, Hirotaka, Lock, Gabriel, Raffatellu, Manuela, Saechao, Cheng, Wangdi, Tamding   +6 more
core   +2 more sources

Continuous-Flow Separation and Efficient Concentration of Foodborne Bacteria from Large Volume Using Nickel Nanowire Bridge in Microfluidic Chip

Micromachines, 2019
Separation and concentration of target bacteria has become essential to sensitive and accurate detection of foodborne bacteria to ensure food safety. In this study, we developed a bacterial separation system for continuous-flow separation and efficient ...
Xiaoting Huo, Qi Chen, Lei Wang, Gaozhe Cai, Wuzhen Qi, Zengzilu Xia, Weijia Wen, Jianhan Lin   +7 more
doaj   +1 more source

Complement and Bacterial Infections: From Molecular Mechanisms to Therapeutic Applications

Journal of Innate Immunity, 2018
Complement is a complex protein network of plasma, and an integral part of the innate immune system. Complement activation results in the rapid clearance of bacteria by immune cells, and direct bacterial killing via large pore-forming complexes.
D. Heesterbeek, Mathieu L Angelier, R. Harrison, S. Rooijakkers   +3 more
semanticscholar   +1 more source