Results 171 to 180 of about 516,620 (290)

Immune effector cell‐associated neurotoxicity syndrome (ICANS) during tebentafusp in metastatic uveal melanoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Laura Schreieder, Laura Jockel, Veronika Zenderowski, Ralf A. Linker, Sebastian Haferkamp, Elisabeth Bumes, Peter Hau, Konstantin Drexler   +7 more
wiley   +1 more source

The XX Factor in Hemophilia: Diagnostic, Therapeutic, and Research Gaps for Women and Girls

Haemophilia, EarlyView.
ABSTRACT Introduction Hemophilia has traditionally been viewed as an X‐linked disorder affecting men and boys, with women and girls labeled as “carriers”, presumed to be clinically unaffected. This paradigm has contributed to under‐recognition, delayed diagnosis, and undertreatment of females with hemophilia‐associated genotypes despite an increasingly
Kelsey Uminski, Ellen Cusano
wiley   +1 more source

The LVI Component Hypothesis: the lymphatic-to-vascular invasion ratio as an enrichment biomarker for therapy with PD-L1×VEGF-A bispecific antibodies. [PDF]

Front Immunol
Kern KA.
europepmc   +1 more source

From Bleeding Control to Health: Implementing Multidimensional and Multidisciplinary Hemophilia Care Into the Era of Therapeutic Innovation

Haemophilia, EarlyView.
ABSTRACT Introduction Over the past decade, hemophilia management has been transformed by modern prophylactic strategies, achieving dramatic reductions in annualized bleeding rates (ABR), often approaching zero. However, the conceptual evolution of hemophilia care toward multidimensional health assessment and comprehensive multidisciplinary management ...
Nicolas Giraud, Yesim Dargaud
wiley   +1 more source

Fc-engineering for improved cancer immunotherapy. [PDF]

Biochem Soc Trans
Borgman E, Le Gall C, Ploegh H, Pishesha N.   +3 more
europepmc   +1 more source

Fc-Silenced CD89 × EGFR Bispecific Antibodies Promote Neutrophil and Macrophage Antitumor Activity. [PDF]

Antibodies (Basel)
Meiser F, Harwardt J, Hahn C, Lustig M, Valerius T, Kolmar H.   +5 more
europepmc   +1 more source

The Haemophilia Health Journey: Experiences and Unmet Care Needs of Caregivers and Their Young Children

Haemophilia, EarlyView.
ABSTRACT Introduction Understanding patients’ and caregivers’ experiences, values and needs is essential to implement patient‐centred care. However, specific insights into how young children with haemophilia and their caregivers experience the entire care trajectory, from diagnosis onwards, remain limited.
Caroline M. A. Mussert, Eva K. Kempers, Evelien S. van Hoorn, Ekin Kerimoğlu, Marijke Melles, Mathieu A. Gielen, Armaĝan Albayrak, Kees T. B. Ahaus, Simone H. Reitsma, Samantha C. Gouw, Marjon H. Cnossen, the PARTITURA study group and SYMPHONY consortium   +11 more
wiley   +1 more source

The clinical trial landscape of bispecific antibodies in non-small cell lung cancer: mechanistic trends and developmental strategies. [PDF]

Front Pharmacol
Li Z, Wang X, Shi Q, Guo Y, Dong G, Liu Z.   +5 more
europepmc   +1 more source

Real‐World Experience With Emicizumab for Haemophilia A From the Physician Perspective in a Real‐World Clinical Setting

Haemophilia, EarlyView.
ABSTRACT Introduction Emicizumab is a bispecific antibody approved for prophylaxis in people with haemophilia A (PwHA). Aim To describe from the physician perspective the characteristics and treatment experiences of PwHA receiving emicizumab. Methods The Adelphi Real World Haemophilia Disease Specific Programme is a cross‐sectional, retrospective data ...
Michael Recht, Chris Blazos, Sophie Lai, Nathan Ball, Ella Morton, Lucy Lee, Juliana M. L. Biondo, Janet S. Lee   +7 more
wiley   +1 more source

Clinical course, risk factors, and therapeutic response in multiple myeloma with central nervous system involvement. [PDF]

Blood Adv
Xiao A, Zanwar S, Lin Y, Kapoor P, Abdallah N, Buadi FK, Binder M, Dispenzieri A, Dingli D, Gertz MA, Gonsalves W, Hayman SR, Kourelis T, Leung N, Muchtar E, Siddiqui M, Tan M, Warsame R, Rajkumar SV, Kumar S.   +19 more
europepmc   +1 more source