Results 191 to 200 of about 26,394 (258)

A New Paradigm of Bispecific Antibodies in Clinical Management of Gastrointestinal Cancers. [PDF]

Oncol Res
Zhao H, Wang X, Fan Z, Sun A, Zhang C, Sun C.   +5 more
europepmc   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Immune cell engagers in lung cancer. [PDF]

Front Immunol
Kang J, Zhang M, He Y, Chen J, Liu X, Lv Q.   +5 more
europepmc   +1 more source

Epitope‐Resolved Digital SERS Profiling of Structurally Dynamic Antigens via a Multi‐Epitope Bispecific Antibody Framework

Advanced Science, Volume 13, Issue 46, 17 August 2026.
A multi‐epitope digital surface‐enhanced Raman spectroscopy framework enables epitope‐resolved immunoprofiling by integrating bispecific antibody fragments with spectrally encoded nanotags. This approach decouples binding events into independent digital channels, allowing structure‐aware antigen analysis.
Jing Wang, Quan Zhou, Kym Lowry, Christopher B. Howard, Matt Trau   +4 more
wiley   +1 more source

Erratum for Li et al., "Bispecific antibodies targeting MPXV A29 and B6 demonstrate efficacy against MPXV infection". [PDF]

J Virol
Li M, Chen J, Wang F, Kuang J, Peng Y, Asghar S, Zhao W, Yang Y, Shen C.   +8 more
europepmc   +1 more source

Determinants of Long‐Term Benefit From High Dose Melphalan With Autologous Stem Cell Transplant in AL Amyloidosis

American Journal of Hematology, Volume 101, Issue 8, Page 1903-1914, August 2026.
ABSTRACT High dose melphalan (HDM) with autologous stem cell transplant is an established treatment for systemic light chain amyloidosis, but its incremental benefit in the era of effective standard intensity therapy is unknown. We retrospectively analyzed 475 transplant‐eligible patients who completed standard intensity treatment with or without HDM ...
Maximilian J. Steinhardt, Ute Hegenbart, Tamer Hellou, Sara Oubari, Murielle Roussel, Rahel Schwotzer, Francis Buadi, David Dingli, Moritz Binder, Taxiarchis Kourelis, Saurabh S. Zanwar, Max J. Rieger, Caroline Morbach, Vladimir Cejka, Bernhard Gerber, Stefan Störk, Hermann Einsele, Shaji Kumar, Morie Gertz, Alexander Carpinteiro, K. Martin Kortum, Eli Muchtar, Angela Dispenzieri, Stefan Schönland   +23 more
wiley   +1 more source

Antibody-based regimens targeting PD-1/PD-L1 and VEGF/VEGFR in advanced or metastatic NSCLC: a meta-analysis of RCTs. [PDF]

Front Immunol
Mao W, Tang Z, Chen Y, Chen Y, Zhang S, Feng X, Zhang S.   +6 more
europepmc   +1 more source

Late-onset progressive multifocal leukoencephalopathy after teclistamab in multiple myeloma: extending the timeline of infectious risk. [PDF]

Haematologica
Chizzoniti D, Ciambelli F, Latargia ML, Canziani L, Godi C, Pavesi F, Zambrotta GMP, Lotesoriere I, Appio L, Bertolli V, Santamaria C, Ballardini F, Cecchetti C, Todisco E.   +13 more
europepmc   +1 more source

Targeting the CD47/SIRPα interaction in cancer: opportunities in non-Hodgkin lymphoma. [PDF]

Expert Opin Investig Drugs
Pagès-Geli C, Weiskopf K.
europepmc   +1 more source

Bispecific and multispecific immune engagers for redirecting innate and adaptive immunity against hematologic cancers. [PDF]

Discov Oncol
Ardah MT, Abdulsahib WK, Abdulsahib WK, Jasim IK, Malathi H, Patro PS, Anand DA, Mukherjee G, Sinha A, Aminqulov S.   +9 more
europepmc   +1 more source