Results 201 to 210 of about 516,620 (290)

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source

CLEC5A/TLR2 bispecific antibody suppresses dengue virus-induced pro-inflammatory cytokines production from macrophages. [PDF]

J Biomed Sci
Wang SH, Kuo WT, Cheng D, Sung PS, Shih SR, Hsieh SL, Wang JR.   +6 more
europepmc   +1 more source

PRAME predicting outcome in uveal melanoma

The Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract Uveal melanoma (UM) is the most common primary intra‐ocular malignancy in adults and carries a high risk of metastatic disease, affecting approximately 50% of patients despite advances in local tumour control. PRAME (PReferentially expressed Antigen in MElanoma) has emerged as a marker for metastatic risk; however, evidence is largely derived ...
Sally Owens, Naomi Walsh, Noel Horgan, Patrick Murtagh, Katie Hanratty, Grainne Finegan, Laura Ivers, John Crown, Susan Kennedy   +8 more
wiley   +1 more source

Target-Specific Dermatological Adverse Event Reporting With T-Cell-Engaging Bispecific Antibodies: A Pharmacovigilance Analysis of FAERS and Canada Vigilance, 2016-2026. [PDF]

Cancer Med
Mandal S, Maji M, Dhali A.
europepmc   +1 more source

Profiling EGFR, c‐MET, and B7H3 co‐expression to guide next‐generation dual‐drug conjugate strategies in colorectal cancer

The Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract Epidermal growth factor receptor (EGFR), cellular mesenchymal‐epithelial transition factor (c‐MET), and B7 homolog 3 (B7H3) are important targets for antibody‐based drug development in colorectal cancer (CRC). To overcome the limitations of single‐target antibody therapies – such as limited efficacy, widespread resistance, narrow patient ...
Yanan Yang, Huiyu Li, Shiwei Xiao, Mengxia Jiao, De Wu, Chunxia Ao, Yanggeling Zhang, Siyuan Yan, Shaomei Sun, Chen Yang, Renhong Tang, Xiyuan Wang, Junqiu Yue   +12 more
wiley   +1 more source

Bispecific Antibodies for Acute Myeloid Leukemia: From Bone Marrow Immune Niche to Clinical Translation. [PDF]

Antibodies (Basel)
Bruzzese A, Martino EA, Caserta S, Alvaro ME, Amodio N, Lucia E, Olivito V, Labanca C, Mendicino F, Morabito F, Vigna E, Gentile M.   +11 more
europepmc   +1 more source

BCMA Antigen Loss Through Acquired TNFRSF17 Deletion in Multiple Myeloma

International Journal of Laboratory Hematology, EarlyView.
Ali Benaboud, Rémi Tilmont, Gauthier Decool, Nicolas Gower, Salomon Manier, Benjamin Podvin   +5 more
wiley   +1 more source

Navigating Asparaginase Treatment for Patients With Acute Lymphoblastic Leukemia: US Consensus Panel Recommendations on the Role of Multidisciplinary Care

American Journal of Hematology, Volume 101, Issue 11, Page 2713-2725, November 2026.
ABSTRACT Asparaginase is a critical treatment component for patients with acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL). However, the successful delivery of asparaginase‐based therapy remains challenging across care settings due to its complex administration, distinct toxicity profile, prolonged treatment duration, and the need for ...
Amir Ali, Grace Elsey, Kayla Fulginiti, Zanette Kanani‐Bradley, Holly R. Kubaney, Sandra Kurtin, Theresa Nguyen, Jennifer Turchina, Charlotte B. Wagner   +8 more
wiley   +1 more source

12th Immunotherapy of Cancer Conference (ITOC12): A meeting report. [PDF]

Hum Vaccin Immunother
Jang S, Manieri MR, Zielinski C, Nuessler V, von Bergwelt-Baildon M, Kobold S.   +5 more
europepmc   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, Volume 123, Issue 11, Page 3079-3105, November 2026.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source