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Radioiodinated monoclonal antibodies
International Journal of Biochemistry, 1988Antibodies were first described by Von Behring almost 100 years ago. Following their early use as putative therapeutic agents in the treatment of infectious and malignant disease (Hericourt and Richet, 1885) their clinical applications dwindled until, at the present day, passive immunotherapy is largely limited to the treatment of such conditions as ...
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Antibodies: monoclonal and polyclonal
Animal Biotechnology, 2020Anchal Singh, Ayushi Mishra, Anju Verma
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Engineering monoclonal antibodies
Nature, 1989Efforts to alter the mAb component of pharmaceuticals have focused on making them more human-lIke and smaller. Ultimately, the smallest molecular recognition unit derived from antibodies may be a single complementarity region.
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Immunology Today, 1988
Abstract Reproducible and efficient production of human monoclonal antibodies of predefined specificity has proved to be a notoriously difficult task. Many variations on basic production techniques now exist and, as Keith Thompson reviews here, the comparative ease with which they can now be made promises to open up numerous new research avenues.
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Abstract Reproducible and efficient production of human monoclonal antibodies of predefined specificity has proved to be a notoriously difficult task. Many variations on basic production techniques now exist and, as Keith Thompson reviews here, the comparative ease with which they can now be made promises to open up numerous new research avenues.
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Understanding monoclonal antibodies
Drug and Therapeutics Bulletin, 2007Elsewhere in this issue, we review new treatments for neovascular age-related macular degeneration,1 of which, â–¼bevacizumab and â–¼ranibizumab are monoclonal antibodies. These are two of a growing number of monoclonal antibodies currently available for therapeutic use in the UK.
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