Results 261 to 270 of about 2,469,529 (358)

Development of monoclonal antibodies against SARS-CoV-2 nucleocapsid protein for COVID-19 antigen detection. [PDF]

Trop Med Health
Mutua MM, Kanoi BN, Nyanjom SG, Musundi S, Makau M, Inoue S, Khamadi SA, Gitaka J, Wandera EA.   +8 more
europepmc   +1 more source

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

Advanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu, Amarnath Marudamuthu, Khadija Kakar, Hamida Hamida, Shruthi Thada, Rohan Gupta, Kiesha Wilson, Taylor Carter, Yin Zhong, Archana Saxena, Xiaoming Yang, Narendra Singh, Philip Brandon Busbee, Jie Li, Monica Garcia‐Buitrago, Prakash Nagarkatti, Mitzi Nagarkatti   +16 more
wiley   +1 more source

Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein. [PDF]

Elife
Waki K, Tani H, Kawahara E, Saga Y, Shimada T, Yamazaki E, Koike S, Morinaga Y, Isobe M, Kurosawa N.   +9 more
europepmc   +1 more source

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

Advanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu, Chengya Huang, Xin Li, Haonan Yu, Yuefeng Xia, Kun Liu, Xingji You, Jingxiang Wu   +7 more
wiley   +1 more source

Perioperative management of transcatheter aortic valve implantation in acquired von Willebrand syndrome secondary to monoclonal gammopathy: a case report. [PDF]

Eur Heart J Case Rep
Filiberti G, Giaj Levra A, Chiarito M, Reimers B, Condorelli G.   +4 more
europepmc   +1 more source

MTFR2‐Mediated Fission Drives Fatty Acid and Mitochondrial Co‐Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis

Advanced Science, EarlyView.
In the tumor margin of hepatocellular carcinoma (HCC), activated hepatic stellate cells upregulate MTFR2, initiating inhibiting DRP1 degradation and mitochondrial fission. This enhances mitochondrial availability and facilitates FAs synthesis via ACC1. Additionally, fission promotes RAC1‐mediated cytoskeletal remodeling and Miro1‐mediated mitochondrial
La Zhang, Baoyong Zhou, Jun Yang, Cong Ren, Jing Luo, Zhenghang Li, Qiang Liu, Zuotian Huang, Zhongjun Wu, Ning Jiang   +9 more
wiley   +1 more source

A Comprehensive Review About the Use of Monoclonal Antibodies in Cancer Therapy. [PDF]

Antibodies (Basel)
Justiz-Vaillant A, Pandit BR, Unakal C, Vuma S, Akpaka PE.   +4 more
europepmc   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Advanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang   +7 more
wiley   +1 more source

Epitope mapping of SARS-CoV-2 Spike protein using naturally-acquired immune responses to develop monoclonal antibodies. [PDF]

Sci Rep
López-Aladid R, Bueno-Freire L, Farriol-Duran R, Porta-Pardo E, Aguilar R, Vidal M, Jiménez A, Cabrera R, Vázquez N, López-Gavín A, Moncunill G, Carrascal M, García T, Lozano M, García-Basteiro AL, Dobaño C, Pazos MD, Estevez MC, Lechuga LM, Torres A, Fernández-Barat L.   +20 more
europepmc   +1 more source