Results 111 to 120 of about 4,984,809 (253)

CD38 antibodies in multiple myeloma: back to the future.

open access: yesBlood, 2018
CD38 is highly and uniformly expressed on multiple myeloma (MM) cells, and at relatively low levels on normal lymphoid and myeloid cells, and in some tissues of nonhematopoietic origin.
N. V. D. van de Donk   +2 more
semanticscholar   +1 more source

Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites. [PDF]

open access: yes, 1985
Three monoclonal antibodies that react with previously undefined antigenic determinants on the clathrin molecule have been produced and characterized. They were isolated from a fusion between myeloma cells and popliteal lymphocytes from SJL mice that had
Brodsky, Frances
core  

Design and Production of Bispecific Antibodies

open access: yesAntibodies, 2019
With the current biotherapeutic market dominated by antibody molecules, bispecific antibodies represent a key component of the next-generation of antibody therapy.
Qiong Wang   +7 more
semanticscholar   +1 more source

Development of novel monoclonal antibodies for blocking NF-κB activation induced by CD2v protein in African swine fever virus

open access: yesFrontiers in Immunology
BackgroundCD2v, a critical outer envelope glycoprotein of the African swine fever virus (ASFV), plays a central role in the hemadsorption phenomenon during ASFV infection and is recognized as an essential immunoprotective protein.
Rongrong Fan   +19 more
doaj   +1 more source

Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility

open access: yesAntibodies, 2018
Antibody-drug conjugates (ADCs) offer a combination of antibody therapy and specific delivery of potent small-molecule payloads to target cells. The properties of the ADC molecule are determined by the balance of its components.
Tero Satomaa   +9 more
doaj   +1 more source

Bispecific CD3/HER2 Targeting FynomAb Induces Redirected T Cell-Mediated Cytolysis with High Potency and Enhanced Tumor Selectivity

open access: yesAntibodies, 2015
CD3 bispecific therapies retargeting T cells to tumors have recently demonstrated striking activity in patients. Several CD3 bispecific antibodies directed against various tumor targets are currently being investigated in the clinic across different ...
Ulrich Wuellner   +9 more
doaj   +1 more source

Antibody-antigen interactions: What is the required time to equilibrium? [PDF]

open access: yes, 2010
The use of antibodies is widespread in many areas including in-vivo and in-vitro diagnostics, quantitative analysis in research laboratories and as therapeutic substances.
Hanna Bjö   +2 more
core   +1 more source

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