Results 11 to 20 of about 3,802,616 (346)

Peptides, Antibodies, Peptide Antibodies and More [PDF]

International Journal of Molecular Sciences, 2019
The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire   +5 more sources

Antibodies and antibody-derived analytical biosensors [PDF]

Essays in Biochemistry, 2016
The rapid diagnosis of many diseases and timely initiation of appropriate treatment are critical determinants that promote optimal clinical outcomes and general public health. Biosensors are now being applied for rapid diagnostics due to their capacity for point-of-care use with minimum need for operator input.
Hannah Byrne, Richard O'Kennedy, Shikha Sharma   +2 more
openaire   +3 more sources

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

Science, 2020
Protective neutralizing antibodies Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neutralizing antibodies, which confer strong protection against severe acute ...
T. Rogers, Fangzhu Zhao, Deli Huang, N. Beutler, Alison Burns, Wan-ting He, Oliver Limbo, C. Smith, G. Song, J. Woehl, Linlin Yang, R. Abbott, Sean Callaghan, Elijah Garcia, Jonathan Hurtado, M. Parren, Linghang Peng, S. Ramirez, James Ricketts, M. Ricciardi, Stephen A. Rawlings, N. Wu, M. Yuan, Davey M. Smith, D. Nemazee, J. Teijaro, J. Voss, I. Wilson, R. Andrabi, Bryan S. Briney, E. Landais, D. Sok, J. Jardine, D. Burton   +33 more
semanticscholar   +1 more source

Animal Models of IgE Anaphylaxis

Biology, 2023
Allergies and atopy have emerged as significant public health concerns, with a progressively increasing incidence over the last two decades. Anaphylaxis is the most severe form of allergic reactions, characterized by a rapid onset and potentially fatal ...
Aurélie Gouel-Chéron, Alice Dejoux, Emma Lamanna, Pierre Bruhns   +3 more
doaj   +1 more source

Development of therapeutic antibodies for the treatment of diseases

Journal of Biomedical Sciences, 2020
It has been more than three decades since the first monoclonal antibody was approved by the United States Food and Drug Administration (US FDA) in 1986, and during this time, antibody engineering has dramatically evolved.
Ruei-Min Lu, Yu-Chyi Hwang, I. Liu, Chi-Chiu Lee, Han-zen Tsai, Hsin-Jung Li, Han‐Chung Wu   +6 more
semanticscholar   +1 more source

Antibodies and tuberculosis

Tuberculosis, 2016
Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine is the only licensed vaccine against TB, but its protective effect does not extend to controlling the development of infectious pulmonary disease in adults. The development
Gavin R. Screaton, Robert J. Wilkinson, Ashley Jacobs, Ashley Jacobs, Juthathip Mongkolsapaya, Helen McShane   +5 more
openaire   +5 more sources

Acknowledgement to Reviewers of Antibodies in 2019

Antibodies, 2020
The editorial team greatly appreciates the reviewers who have dedicated their considerable time andexpertise to the journal’s rigorous editorial process over the past 12 months[...]
Antibodies Editorial Office
doaj   +1 more source

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

Nature Communications, 2021
Monoclonal antibodies targeting a variety of epitopes have been isolated from individuals previously infected with SARS-CoV-2, but the relative contributions of these different antibody classes to the polyclonal response remains unclear.
Allison J. Greaney, Tyler N. Starr, C. Barnes, Y. Weisblum, F. Schmidt, M. Caskey, C. Gaebler, A. Cho, Marianna Agudelo, Shlomo Finkin, Zijun Wang, D. Poston, F. Muecksch, T. Hatziioannou, P. Bieniasz, D. Robbiani, M. Nussenzweig, P. Bjorkman, J. Bloom   +18 more
semanticscholar   +1 more source

Isolation of a human SARS-CoV-2 neutralizing antibody from a synthetic phage library and its conversion to fluorescent biosensors

Scientific Reports, 2022
Since late 2019, the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resultant spread of COVID-19 have given rise to a worldwide health crisis that is posing great challenges to public health and clinical treatment, in ...
Haimei Li, Bo Zhu, Baowei Li, Limei Chen, Xuerao Ning, Hang Dong, Jingru Liang, Xueying Yang, Jinhua Dong, Hiroshi Ueda   +9 more
doaj   +1 more source

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

Science, 2020
An antibody defense against COVID-19 One of the responses of the immune system to invading viruses is the production of antibodies. Some of these are neutralizing, meaning that they prevent the virus from being infectious, and can thus be used to treat ...
Yan Wu, Feiran Wang, Chenguang Shen, Weiyu Peng, Delin Li, Cheng Zhao, Z. Li, Shihua Li, Y. Bi, Yang Yang, Y. Gong, Haixia Xiao, Z. Fan, Shuguang Tan, Guizhen Wu, W. Tan, Xuancheng Lu, Changfa Fan, Qihui Wang, Yingxia Liu, Chen Zhang, J. Qi, G. Gao, F. Gao, Lei Liu   +24 more
semanticscholar   +1 more source